candesartan

Known as: 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid, 2-Ethoxy-1-(P-(O-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid 
A synthetic, benzimidazole-derived angiotensin II receptor antagonist prodrug with antihypertensive activity. Candesartan selectively competes with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The Candesartan Antihypertensive Survival Evaluation in Japan Trial was designed to compare the long-term effects of the… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Results of previous studies suggest that renin-angiotensin system blockers might reduce the burden of diabetic… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES We assessed the risk of adverse cardiovascular (CV) outcomes associated with atrial fibrillation (AF) in the… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Chronic heart failure (CHF) is an important cause of hospital admission and death. Poor adherence to medication is… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Half of patients with chronic heart failure (CHF) have preserved left-ventricular ejection fraction (LVEF), but few… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Patients with chronic heart failure (CHF) are at high risk of cardiovascular death and recurrent hospital admissions… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Angiotensin II type 1 receptor blockers have favourable effects on haemodynamic measurements, neurohumoral activity… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Angiotensin-converting-enzyme (ACE) inhibitors improve outcome of patients with chronic heart failure (CHF). A… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVES To assess and compare the effects of candesartan or lisinopril, or both, on blood pressure and urinary albumin… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND We investigated the effects of candesartan (an angiotensin II antagonist) alone, enalapril alone, and their… (More)
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