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candesartan

Known as: 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid, 2-Ethoxy-1-(P-(O-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid 
A synthetic, benzimidazole-derived angiotensin II receptor antagonist prodrug with antihypertensive activity. Candesartan selectively competes with… 
National Institutes of Health

Related topics

Related topics

21 relations
Angiotensin 2 Receptor Antagonists [MoA]Angiotensin 2 Type 1 Receptor Antagonists [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Broader (4)

Angiotensin II Type 1 Receptor BlockersAntihypertensive AgentsBenzimidazolesTetrazoles

Narrower (3)

AtacandCV-11974candesartan cilexetil

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Quality by Design Approach (QbD) for the Simultaneous Determination of Anti-Hypertensive Drugs (Candesartan, Irbesartan and Hydrochlorothiazide) by RP-HPLC
A new reverse-phase liquid chromatographic technique has been developed for the separation and determination of anti-hypertensive… 
2014
2014
Determination of Candesartan and Hydrochlorothiazide in Human Plasma by HPLC Coupled with Mass Spectrometry
Quantitative determination of hydrochlorothiazide (HCTZ) and candesartan (CDS) in human plasma in volunteers was performed using… 
2011
2011
[Dynamics of primary hemostasis activity in patients with arterial hypertension and metabolic syndrome treated with candesartan].
The aim of the study was to elucidate normalizing effect of candesartan on disturbed thrombocytic hemostasis in patients with… 
2011
2011
A novel RP-HPLC method for the analysis of levetiracetam in formulations
A simple, rapid RP-HPLC method was developed and validated for assay of Levetiracetam in formulations. Isocratic elution at a… 
2010
2010
Role of renin-angiotensin system blockades in reciprocal relationship between insulin resistance and endothelial dysfunction.
To the Editor: Azekoshi et al1 demonstrated that the enhanced production of angiotensin II by free fatty acid in mononuclear and… 
2008
2008
Telmisartan and Carotid Intima-Media Thickness Regression: A Class Effect of Angiotensin-Receptor Blockers?
Telmisartan and Carotid Intima-Media Thickness Regression: A Class Effect of Angiotensin-Receptor Blockers? 
2007
2007
AT 1 receptor blockade prevents interstitial and glomerular apoptosis but not fibrosis in pigs with neonatal induced partial unilateral ureteral obstruction
Anni Eskild-Jensen, Lene Fogt Paulsen, Lise Wogensen, Ping Olesen, Lea Pedersen, Jørgen Frøkiær, and Jens Randel Nyengaard… 
2004
2004
Trial of Preventing Hypertension (TROPHY): design and 2-year progress report.
The article “Trial of Preventing Hypertension (TROPHY): Design and 2-Year Progress Report” by Stevo Julius et al in this issue of… 
1999
1999
The angiotensin II AT1-receptor antagonist candesartan improves functional recovery and reduces the no-reflow area in reperfused ischemic rat hearts.
It is not yet clear if cardiac angiotensin II is involved in the pathophysiology of myocardial ischemia/ reperfusion injury. The… 
1999
1999
The Angiotensin II AT1 Receptor Antagonist Candesartan at Antihypertensive Plasma Concentrations Reduces Damage Induced by Ischemia–Reperfusion
The aim of this study was to investigate if the angiotensin II AT1 receptor antagonist candesartan in antihypertensive plasma…