cancer-predisposing genes

Known as: Cancer Susceptibility Gene, Cancer-Predisposing Gene, Susceptibility Gene 
Mutated forms of genes which encode proteins that are essential for the control and maintenance of normal cellular processes. Inherited or somatic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Nonatherosclerotic spontaneous coronary artery dissection (NA-SCAD) is underdiagnosed and an important cause of… (More)
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Highly Cited
2009
Highly Cited
2009
Through complete sequencing of the protein-coding genes in a patient with familial pancreatic cancer, we identified a germline… (More)
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Review
2008
Review
2008
Psychiatric and neurologic disorders take an enormous toll on society. Alleviating the devastating symptoms and consequences of… (More)
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2005
2005
To date, germline mutations have been found in three candidate genes for hereditary prostate cancer: ELAC2 at 17p11, RNASEL at… (More)
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Highly Cited
2004
Highly Cited
2004
Genetic variation in dysbindin (DTNBP1: dystrobrevin-binding protein 1) has recently been shown to be associated with… (More)
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Highly Cited
2003
Highly Cited
2003
Current debate focuses on the relevance of linkage disequilibrium (LD), ethnicity and underlying haplotype structure to the… (More)
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Review
2001
Review
2001
Insulin receptor substrate (IRS) molecules are key mediators in insulin signaling and play a central role in maintaining basic… (More)
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Review
1999
Review
1999
Apolipoprotein E is a key regulator of plasma lipid levels. Our appreciation of its role continues to expand as additional… (More)
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Highly Cited
1996
Highly Cited
1996
The DNA mismatch repair genes MSH2 and MLH1 have been shown to account for a major share of hereditary non-polyposis colorectal… (More)
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Highly Cited
1994
Highly Cited
1994
Genetic predisposition to neoplasia often involves tumor suppressor genes. One such model of hereditary renal carcinoma was… (More)
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