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cancer-predisposing genes

Known as: Cancer Susceptibility Gene, Cancer-Predisposing Gene, Susceptibility Gene 
Mutated forms of genes which encode proteins that are essential for the control and maintenance of normal cellular processes. Inherited or somatic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND The prevalence and spectrum of predisposing mutations among children and adolescents with cancer are largely unknown… Expand
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Highly Cited
2014
Highly Cited
2014
Background—Nonatherosclerotic spontaneous coronary artery dissection (NA-SCAD) is underdiagnosed and an important cause of… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is… Expand
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Highly Cited
2009
Highly Cited
2009
Through complete sequencing of the protein-coding genes in a patient with familial pancreatic cancer, we identified a germline… Expand
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Review
2008
Review
2008
Psychiatric and neurologic disorders take an enormous toll on society. Alleviating the devastating symptoms and consequences of… Expand
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Highly Cited
2007
Highly Cited
2007
Summary The heritability of B cell chronic lymphocytic leukemia (CLL) is relatively high; however, no predisposing mutation has… Expand
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Highly Cited
2004
Highly Cited
2004
Genetic variation in dysbindin (DTNBP1: dystrobrevin-binding protein 1) has recently been shown to be associated with… Expand
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Highly Cited
2003
Highly Cited
2003
Current debate focuses on the relevance of linkage disequilibrium (LD), ethnicity and underlying haplotype structure to the… Expand
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Review
2001
Review
2001
Insulin receptor substrate (IRS) molecules are key mediators in insulin signaling and play a central role in maintaining basic… Expand
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Review
1999
Review
1999
Apolipoprotein E is a key regulator of plasma lipid levels. Our appreciation of its role continues to expand as additional… Expand
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