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calcineurin phosphatase

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
BACKGROUND Tacrolimus exerts its immunosuppressive effect through inhibition of the intracellular enzyme calcineurin phosphatase… Expand
2008
2008
BACKGROUND Regardless of the extensive worldwide use of calcineurin inhibitors, little is known about the behavior of calcineurin… Expand
Review
2007
Review
2007
Cyclosporine A (CsA) is metabolized into a vast spectrum of metabolites. The potential immunosuppressive action of CsA's… Expand
2006
2006
The pharmacodynamic (PD) action of tacrolimus (FK) within the T-cell is inhibition of calcineurin phosphatase (CaN… Expand
2006
2006
Cyclosporin and tacrolimus remain the cornerstone immunosuppressive drugs in organ transplantation. Dosing and monitoring these… Expand
2005
2005
Calcineurin phosphatase (CaN) activity has been the focus of several recent studies on renal transplant patients as the… Expand
2004
2004
BACKGROUND The calcineurin inhibitors cyclosporine and tacrolimus are used as primary immunosuppressive drugs in transplant… Expand
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1999
1999
Prolactin (PRL) is produced in human thymocytes, T-cells and endometrium. In these extrapituitary tissues, PRL gene transcription… Expand
1996
1996
Recent reports have shown that cyclosporine (CsA)-treated patients have abundant calcineurin phosphatase (CN) activity in vivo… Expand
Highly Cited
1995
Highly Cited
1995
Despite increasing information about the mechanism of action of cyclosporine A (CsA), little is known about the way lymphocytes… Expand