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calcineurin phosphatase

National Institutes of Health

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Broader (1)

Phosphoric Monoester Hydrolases

Papers overview

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2016
2016
New strategy of tacrolimus administration in animal model based on tacrolimus-loaded microspheres.
2010
2010
Gene expression analysis of calcineurin isoforms in T-lymphocytes--a method applied on kidney-transplant recipients.
Review
2007
Review
2007
A review of the immunosuppressive activity of cyclosporine metabolites: new insights into an old issue.
Cyclosporine A (CsA) is metabolized into a vast spectrum of metabolites. The potential immunosuppressive action of CsA's… 
2006
2006
The calcineurin activity profiles of cyclosporin and tacrolimus are different in stable renal transplant patients
Cyclosporin and tacrolimus remain the cornerstone immunosuppressive drugs in organ transplantation. Dosing and monitoring these… 
2006
2006
Calcineurin activity in tacrolimus-treated renal transplant patients early after and 5 years after transplantation.
2005
2005
Comparison of the temporal profile of calcineurin inhibition by cyclosporine and tacrolimus in renal transplant patients.
2004
2004
Validation of the calcineurin phosphatase assay.
BACKGROUND The calcineurin inhibitors cyclosporine and tacrolimus are used as primary immunosuppressive drugs in transplant… 
1999
1999
The human prolactin gene upstream promoter is regulated in lymphoid cells by activators of T-cells and by cAMP.
Prolactin (PRL) is produced in human thymocytes, T-cells and endometrium. In these extrapituitary tissues, PRL gene transcription… 
1996
1996
Cyclosporine inhibition of leukocyte calcineurin is much less in whole blood than in culture medium.
Recent reports have shown that cyclosporine (CsA)-treated patients have abundant calcineurin phosphatase (CN) activity in vivo… 
Highly Cited
1995
Highly Cited
1995
Cyclosporine inhibition of calcineurin activity in human leukocytes in vivo is rapidly reversible.
Despite increasing information about the mechanism of action of cyclosporine A (CsA), little is known about the way lymphocytes… 
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