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butyrolactone I

Known as: alpha-oxo-beta-(4-hydroxyphenyl)-gamma-(4-hydroxy-m-3,3-dimethylallylbenzyl)-gamma-methoxycarbonyl-gamma-butyrolactone 
 

Topic mentions per year

Topic mentions per year

1993-2016
0246819932016

Related topics

Related topics

2 relations

Broader (2)

4-ButyrolactoneProtein Kinase Inhibitors

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
butyrolactone I
Protein Kinase Inhibitors
4-Butyrolactone

Papers overview

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2008
2008
Butyrolactone I derivatives from Aspergillus terreus carrying an unusual sulfate moiety.
In our ongoing search for new bioactive metabolites from microbial resources, Aspergillus terreus (HKI0499) was examined by… (More)
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2001
2001
Bovine oocytes treated prior to in vitro maturation with a combination of butyrolactone I and roscovitine at low doses maintain a normal developmental capacity.
Butyrolactone I (BL-I) and Roscovitine (ROS), two specific and potent inhibitors of M-phase promoting factor (MPF) kinase… (More)
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2000
2000
Butyrolactone I reversibly inhibits meiotic maturation of bovine oocytes,Without influencing chromosome condensation activity.
In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases, was shown to block germinal… (More)
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2000
2000
Bovine oocyte and embryo development following meiotic inhibition with butyrolactone I.
In this study we have shown that butyrolactone I (BL-I), a potent inhibitor of cyclin-dependent kinases, inhibits meiotic… (More)
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Highly Cited
1999
Highly Cited
1999
Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells
Centrosome duplication is indispensable for the formation of the bipolar mitotic spindle. Surprisingly, even if DNA replication… (More)
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1998
1998
Effect of butyrolactone I on the producing fungus, Aspergillus terreus.
Butyrolactone I [alpha-oxo-beta-(p-hydroxyphenyl)-gamma-(p-hydroxy-m-3, 3-dimethylallyl-benzyl)-gamma-methoxycarbonyl-gamma… (More)
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Highly Cited
1997
Highly Cited
1997
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.
Cyclin-dependent kinases (cdk) play an essential role in the intracellular control of the cell division cycle (cdc). These… (More)
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1996
1996
Antitumor effects of butyrolactone I, a selective cdc2 kinase inhibitor, on human lung cancer cell lines.
Butyrolactone I, which is a naturally occurring specific inhibitor of the cdc2 kinase family, showed antitumor effects on several… (More)
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1994
1994
A cyclin-dependent kinase inhibitor, butyrolactone I, inhibits phosphorylation of RB protein and cell cycle progression.
Butyrolactone I is a selective inhibitor of the cyclin-dependent kinase (cdk) family. It inhibits both cdk2 and cdc2 kinase, but… (More)
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1993
1993
Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase.
We screened cdc2 kinase inhibitors from cultured mediums of micro organisms using purified mouse cyclin B-cdc2 kinase and a… (More)
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