buthionine sulfoximine/melphalan

Known as: BSO/L-PAM 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
01219862018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Glutathione is an important antioxidant in the brain that appears to be decreased, in conjunction with mitochondrial complex I… (More)
Is this relevant?
2008
2008
Arsenic trioxide (ATO) affects many biological processes such as cell proliferation, apoptosis, differentiation and angiogenesis… (More)
Is this relevant?
2003
2003
The role of antioxidants in maintaining the functional integrity of adrenocortical cells during in vitro exposure to endosulfan… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
2002
2002
Patients with high-risk neuroblastoma (NB) initially respond to aggressive, alkylator-based therapy only to die from recurrent… (More)
  • figure 1
  • table 1
  • table 2
Is this relevant?
1994
1994
MCF-7 human breast cancer cells possess high levels of O6-alkylguanine-DNA alkyltransferase and moderate levels of glutathione… (More)
Is this relevant?
1994
1994
Buthionine sulfoximine (BSO) is an inhibitor of glutathione synthesis that can deplete intracellular glutathione and reverse… (More)
Is this relevant?
1993
1993
Taxol is a naturally occurring chemotherapeutic agent that is active against a variety of tumors. Taxol is believed to act by… (More)
  • figure I
  • figure 2
  • figure 5
  • figure 3
  • figure 4
Is this relevant?
1988
1988
A series of studies was performed in tumor bearing mice to evaluate the impact of glutathione (GSH) depletion by L-buthionine… (More)
Is this relevant?
1986
1986
L-Buthionine-S,R-sulfoximine (L-BSO), a selective inhibitor of glutathione synthesis, exhibited the capacity to deplete embryonic… (More)
Is this relevant?
1986
1986
Two and four treatments of 5 mmol kg-1 of buthionine sulfoximine (BSO) at an interval of 12 h depleted the glutathione (GSH… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?