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bufuralol 1'-hydroxylase

Known as: bufuralol 1'-monooxygenase 
 
National Institutes of Health

Papers overview

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2008
2008
Beagle dogs are commonly used for toxicological and pharmacological studies of drug candidates in the pharmaceutical industry… Expand
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2000
2000
The effect of bisphenol A (BPA) on the kinetics of cytochrome P450 (P450)-dependent monooxygenases in rat liver microsomes was… Expand
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1999
1999
NADPH-cytochrome P-450 oxidoreductase (CPR) is essential for the catalytic activity of cytochrome P-450 (P-450). On a molar basis… Expand
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1998
1998
Precision-cut human liver slices are an important tool for defining the metabolism and hepatotoxicity of drug candidates early in… Expand
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1998
1998
1. We examined the effect of two chloro-s-triazines (atrazine and simazine) on hepatic microsomal cytochrome P450 enzymes in rat… Expand
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1997
1997
Human cytochrome P450 2D6 metabolizes more than 50 common drugs and is polymorphically expressed, with 5-10% of the population… Expand
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Highly Cited
1995
Highly Cited
1995
The metabolism of probe substrates of phase I and phase II enzymes in vitro were compared in hepatic subcellular fractions from… Expand
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1989
1989
This study has characterised the distribution of bufuralol 1'-hydroxylase activity in various organs of male and female Sprague… Expand
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Highly Cited
1987
Highly Cited
1987
Bufuralol, debrisoquine, and dextromethorphan are three prototype substrates of the common genetic deficiency of oxidative drug… Expand
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1986
1986
The kinetics of bufuralol 1'-hydroxylase activity of hepatic microsomal fractions have been determined in female DA and Fischer… Expand
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