bufuralol 1'-hydroxylase

Known as: bufuralol 1'-monooxygenase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2008
012319852008

Papers overview

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2008
2008
Beagle dogs are commonly used for toxicological and pharmacological studies of drug candidates in the pharmaceutical industry… (More)
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2000
2000
The effect of bisphenol A (BPA) on the kinetics of cytochrome P450 (P450)-dependent monooxygenases in rat liver microsomes was… (More)
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1999
1999
NADPH-cytochrome P-450 oxidoreductase (CPR) is essential for the catalytic activity of cytochrome P-450 (P-450). On a molar basis… (More)
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1998
1998
CYP2D15 is the canine ortholog of human CYP2D6, the human CYP2D isoform involved in the metabolism of drugs such as… (More)
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1998
1998
Precision-cut human liver slices are an important tool for defining the metabolism and hepatotoxicity of drug candidates early in… (More)
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1998
1998
1. We examined the effect of two chloro-s-triazines (atrazine and simazine) on hepatic microsomal cytochrome P450 enzymes in rat… (More)
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1995
1995
The metabolism of probe substrates of phase I and phase II enzymes in vitro were compared in hepatic subcellular fractions from… (More)
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1994
1994
1. The effects of in vivo administration of H2 blockers, cimetidine and ranitidine (0.6 mmol/kg body weight/day, for 5 days), on… (More)
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1993
1993
(R)- and (S)-fluoxetine were found to be competitive inhibitors of P450 2D6-mediated bufuralol 1'-hydroxylation in vitro… (More)
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Highly Cited
1987
Highly Cited
1987
Bufuralol, debrisoquine, and dextromethorphan are three prototype substrates of the common genetic deficiency of oxidative drug… (More)
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