brusatol

Known as: (11 beta,12 alpha,15 beta)-13,20-epoxy-3,11,12- trihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)- 2,16-dioxopicras-3-en-21-oic acid, methyl ester 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
051019792018

Papers overview

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2016
2016
NF-E2-related factor 2 (Nrf2) has been identified as a master regulatory factor in the protection of cells from oxidative and… (More)
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2016
2016
The KEAP1/Nrf2 pathway senses and responds to changes in intracellular oxidative stress. Mutations that result in constitutive… (More)
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2015
2015
The transcription factor Nrf2 regulates the basal and inducible expression of a battery of cytoprotective genes. Whereas numerous… (More)
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2015
2015
Brusatol is a natural terpenoid that is capable of inducing a variety of biological effects. We presently report that this… (More)
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2013
2013
Brucea javanica (L.) Merr. is a medicine plant distributed widely throughout Asia where its bitter fruits have been used… (More)
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Highly Cited
2011
Highly Cited
2011
The major obstacle in cancer treatment is the resistance of cancer cells to therapies. Nrf2 is a transcription factor that… (More)
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2004
2004
Brusatol, a quassinoid isolated from the fruit of Brucea javanica, induces cell differentiation with various leukemic cell lines… (More)
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1987
1987
The quassinoids bruceoside-A [1], brusatol [2], and bruceolide [3] were tested for antimalarial activity in vitro against the… (More)
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1983
1983
A series of quassinoids were observed to be potent inhibitors of induced inflammation and arthritis in rodents. Brusatol afforded… (More)
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1981
1981
The mechanism by which brusatol inhibits protein synthesis in rabbit reticulocytes has been investigated. When added to… (More)
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