brivudine

Known as: Uridine, 5-(2-bromoethenyl)-2'-deoxy-, (E)-, BVDU, 5-(2-bromoethenyl)-2'-deoxyuridine 
A uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The human immunodeficiency virus (HIV) has now been established as the causative agent of the acquired immunodeficiency syndrome… (More)
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Review
2009
Review
2009
Thymidine phosphorylase (TP), also known as "platelet-derived endothelial cell growth factor" (PD-ECGF), is an enzyme, which is… (More)
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2005
2005
The absence of any formally licensed antiadenovirus drugs and the increasing incidence of life-threatening adenovirus infections… (More)
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Review
2004
Review
2004
The current armamentarium for the chemotherapy of viral infections consists of 37 licensed antiviral drugs. For the treatment of… (More)
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2003
2003
Nucleoside analogs act as prodrugs that must be converted to 5'-phosphates by intracellular kinases to become active in the… (More)
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Highly Cited
2001
Highly Cited
2001
The chemotherapy of virus infections has definitely come of age. There are now 15 antiviral agents that have been formally… (More)
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2001
2001
The presence of Epstein-Barr virus (EBV) in the tumor cells of some EBV-associated malignancies may facilitate selective killing… (More)
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Highly Cited
1997
Highly Cited
1997
To ascertain whether concomitant expression of Escherichia coli deaminase (CD) and herpes simplex virus type-1 thymidine kinase… (More)
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Review
1997
Review
1997
This article describes several approaches to a selective therapy of virus infections: (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU… (More)
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Review
1993
Review
1993
The target protein (enzyme) with which antiviral agents interact determines their antiviral activity spectrum. Based on their… (More)
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