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bretazenil
Known as:
9H-Imidazo(1,5-a)pyrrolo(2,1-c)(1,4)benzodiazepine-1-carboxylic acid, 8-bromo-11,12,13,13a-tetrahydro-9-oxo-,1,1-dimethylethyl ester, (S)-
, t-butyl-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo(1,5-a)-pyrrolo(2,1-c)(1,4)benzodiazepine-1-carboxylate
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Anticonvulsants
Benzodiazepinones
Narrower (1)
Ro 16-6028
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Mechanisms Underlying Tolerance after Long-Term Benzodiazepine Use: A Future for Subtype-Selective GABAA Receptor Modulators?
C. Vinkers
,
B. Olivier
Advances in Pharmacological Sciences
2012
Corpus ID: 2997654
Despite decades of basic and clinical research, our understanding of how benzodiazepines tend to lose their efficacy over time…
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Review
2011
Review
2011
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism.
Qi Wu
,
R. Palmiter
European Journal of Pharmacology
2011
Corpus ID: 25775878
Highly Cited
2009
Highly Cited
2009
Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation
Qi Wu
,
Maureen P. Boyle
,
R. Palmiter
Cell
2009
Corpus ID: 18488313
Highly Cited
2008
Highly Cited
2008
Comparison of the Novel Subtype-Selective GABAA Receptor-Positive Allosteric Modulator NS11394 [3′-[5-(1-Hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with Diazepam, Zolpidem…
Gordon Munro
,
J. Lopez-Garcia
,
+5 authors
Naheed Mirza
Journal of Pharmacology and Experimental…
2008
Corpus ID: 36490884
Spinal administration of GABAA receptor modulators, such as the benzodiazepine drug diazepam, partially alleviates neuropathic…
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Highly Cited
2006
Highly Cited
2006
An Inverse Agonist Selective for α5 Subunit-Containing GABAA Receptors Enhances Cognition
G. Dawson
,
K. Maubach
,
+14 authors
J. Atack
Journal of Pharmacology and Experimental…
2006
Corpus ID: 6410599
α5IA is a compound that binds with equivalent subnanomolar affinity to the benzodiazepine (BZ) site of GABAA receptors containing…
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Highly Cited
2006
Highly Cited
2006
Decreases in nestlet shredding of mice by serotonin uptake inhibitors: comparison with marble burying.
Xia Li
,
Denise Morrow
,
J. Witkin
Life Science
2006
Corpus ID: 13032347
Review
2005
Review
2005
GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon
A. Guidotti
,
J. Auta
,
+5 authors
E. Costa
Psychopharmacology
2005
Corpus ID: 25147595
RationaleCortical γ-aminobutyric acid (GABA)ergic neurons contribute to the orchestration of pyramidal neuron population firing…
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Highly Cited
2003
Highly Cited
2003
Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors.
E. Cagetti
,
Jing Liang
,
I. Spigelman
,
R. Olsen
Molecular Pharmacology
2003
Corpus ID: 26308436
One of the pharmacological targets of ethanol is the GABAA receptor (GABAR), whose function and expression are altered after…
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Highly Cited
2001
Highly Cited
2001
Enhanced Anticonvulsant Activity of Neuroactive Steroids in a Rat Model of Catamenial Epilepsy
D. Reddy
,
M. Rogawski
Epilepsia
2001
Corpus ID: 30284480
Summary: Purpose: Perimenstrual catamenial epilepsy may in part be due to withdrawal of the endogenous progesterone‐derived…
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Highly Cited
1993
Highly Cited
1993
Triazolam is more efficacious than diazepam in a broad spectrum of recombinant GABAA receptors.
I. Ducic
,
G. Puia
,
S. Vicini
,
E. Costa
European Journal of Pharmacology
1993
Corpus ID: 5658971
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