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bohemine

Known as: 6-benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine 
National Institutes of Health

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1 relation

Broader (1)

Purines

Papers overview

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2010
2010
Human galectin‐3 interacts with two anticancer drugs
Human galectin‐3 (hGal‐3) is a mammalian lectin involved in regulation of RNA splicing, apoptosis, cell differentiation, and… 
2010
2010
The radiosensitising effect of olomoucine derived synthetic cyclin-dependent kinase inhibitors.
Bohemine and roscovitine are the most important representatives of the group of compounds structurally derived from olomoucine… 
2005
2005
Protein Fingerprints of Anti-cancer Effects of Cyclin-dependent Kinase Inhibition: Identification of Candidate Biomarkers Using 2-D Liquid Phase Separation Coupled to Mass Spectrometry
The purpose of this study was to apply a recently introduced proteomic based approach to identify candidate biomarkers of the… 
2004
2004
Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis.
Determination of pharmacokinetic properties in the intact animal remains a major bottleneck in drug discovery. Cassette dosing… 
2003
2003
In vitro glycosidation potential towards olomoucine-type cyclin-dependent kinase inhibitors in rodent and primate microsomes.
Interspecies differences in glycosidation potential in mammalian tissues represent a factor contributing to ambiguity when… 
2003
2003
INHIBITION OF CYTOKININ-GLUCOSE CONJUGATION IN DEROOTED RADISH, TOBACCO AND BEAN SEEDLINGS
Four inhibitors of cyclin-dependent kinases, olomoucine, bohemine, roscovitine and isopropyl-olomoucine were tested for their… 
2002
2002
In vitro biotransformation of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine by mouse liver microsomes
1. Biotransformation pathways of the cyclin-dependent kinase inhibitor 6-benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine… 
2002
2002
Application of Proteomics in the Search for Novel Proteins Associated with the Anti-cancer Effect of the Synthetic Cyclin-dependent Kinases Inhibitor, Bohemine
The purpose of this study was to use the proteomics approach, which is based on high resolution two-dimensional electrophoresis… 
2001
2001
In vivo metabolism of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine in mice: glucosidation as the principal metabolic route.
Synthetic cyclin-dependent kinase inhibitors have recently been referred to as effective antiproliferative agents. This study was… 
2001
2001
Effect of meta-topolin and bohemine derived from benzylaminopurine on PSII function in artificially senescing wheat leaves
Cytokinin 6-benzylaminopurine (BA) is known to slow down chlorophyll and protein degradation and decrease of photosynthetic… 
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