bleomycinic acid
National Institutes of Health
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Three bleomycin (BLM)-resistant sublines were isolated from a human head and neck squamous cell carcinoma cell line (A-253…
Rabbit antisera highly specific to the bleomycinic acid moiety of bleomycins were obtained by immunizing with a conjugate of…
Spin-labeled derivatives of bithiazole and bleomycin were studied with respect to their uptake and localization in KB cells in…
The bleomycins, discovered in 1966 by Umezawa and colleagues [12], have been the focus of intense interest for a number of years…
The structures of bleomycins, including their stereochemistry as shown in Figure 1, were conclusively determined by a study in…
The bleomycins are antitumor agents composed of various cationic amides of a common inactive bleomycinic acid. At 1 mug/ml at 37…
Previously an enzyme, named acylagmatine amidohydrolase, hydrolyzing bleomycin B2 to bleomycinic acid and agmatine was found in…