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bisnaphthalimidopropylspermidine

Known as: BNIPSpd, bis-naphthalimidopropyl spermidine 
 
National Institutes of Health

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Related topics

3 relations

Broader (2)

Quinolonesspermidine
analogs & derivatives

Papers overview

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2018
2018
Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells.
Bisnaphthalimides are DNA intercalators of potential use as chemotherapeutics but for which the range of mechanism of action is… Expand
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2011
2011
The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in Caco-2 colon epithelial cells
Bisnaphthalimido compounds bis-intercalate to DNA via the major groove and are potentially potent cancer therapeutics. Previously… Expand
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2009
2009
Bisnaphthalimidopropyl spermidine induces apoptosis within colon carcinoma cells.
Bisnaphthalimido compounds bisintercalate to DNA via the major groove and are potentially potent cancer therapeutics. We… Expand
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2007
2007
The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum.
Bisnaphthalimidopropyl derivatives (BNIPSpd, BNIPDaoct, BNIPDanon, BNIPDadec, BNIPDpta and BNIPDeta) were synthesised in yields… Expand
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2005
2005
Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes.
The natural polyamines are ubiquitous polycationic compounds that play important biological functions in cell growth and… Expand
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2005
2005
Synthesis and biological activities of bisnaphthalimido polyamines derivatives: cytotoxicity, DNA binding, DNA damage and drug localization in breast cancer MCF 7 cells.
New bisoxynaphthalimidopolyamines (BNIPOPut, BNIPOSpd and BNIPOSpm) were synthesized. Their cytotoxic properties were evaluated… Expand
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2004
2004
Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells.
Three polyamine derivatives assigned as bis-naphthalimidopropyl putrescine (BNIPPut), spermidine (BNIPSpd) and spermine (BNIPSpm… Expand
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2000
2000
The synthesis and in vitro cytotoxic studies of novel bis-naphthalimidopropyl polyamine derivatives.
Bis-naphthalimidopropyl putrescine (BNIPPut), spermidine (BNIPSpd), spermine (BNIPSpm) and oxa-putrescine (BNIPOPut) were… Expand
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