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biostim/melphalan/prednisone/vincristine

Known as: Biostim/L-PAM/PRED/VCR 
National Institutes of Health

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MelphalanPrednisoneVincristinebiostim

Papers overview

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2020
2020
Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors
Allopregnanolone (3α5α-P), pregnanolone, and their synthetic derivatives are potent positive allosteric modulators (PAMs) of… 
2018
2018
Overexpression of HIF-1α contributes to melphalan resistance in multiple myeloma cells by activation of ERK1/2, Akt, and NF-κB
Multiple myeloma (MM) commonly displays multidrug resistance and is associated with poor prognosis. Therefore, it is important to… 
2018
2018
Organic arsenicals target thioredoxin reductase followed by oxidative stress and mitochondrial dysfunction resulting in apoptosis.
2018
2018
PAM-OBG: A monoamine oxidase B specific prodrug that inhibits MGMT and generates DNA interstrand crosslinks, potentiating temozolomide and chemoradiation therapy in intracranial glioblastoma
Via extensive analyses of genetic databases, we have characterized the DNA-repair capacity of glioblastoma with respect to… 
2015
2015
Effective gene delivery into human stem cells with a cell-targeting Peptide-modified bioreducible polymer.
Stem cells are poorly permissive to non-viral gene transfection reagents. In this study, we explored the possibility of improving… 
2015
2015
Hydrolysis-Sensitive Dithiolethione Prodrug Micelles.
Prodrug micelles carrying 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT-OH), a compound possessing chemopreventive properties… 
2013
2013
Nonviral gene therapy in vivo with PAM-RG4/apoptin as a potential brain tumor therapeutic
Background Glioma is still one of the most complicated forms of brain tumor to remove completely due to its location and the lack… 
2005
2005
Genotoxic changes in the pulmonary alveolar macrophages of mice, rats and hamsters treated with tobacco smoke
To determine whether tobacco smoke (TS) is genotoxic for lung tissue macrophages (pulmonary alveolar macrophages, PAM) as a… 
1994
1994
1‐Acyl‐2‐lysophosphatidylcholine transport across the blood—retina and blood—brain barrier
1987
1987
Response of drug-sensitive and -resistant L1210 leukemias to high-dose chemotherapy.
Alkylating agent-sensitive and -resistant L1210 leukemia cell lines were used to determine the tumor response to dose levels of… 
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