bilateral retinoblastoma

Retinoblastoma involving both eyes. This occurs in the majority of patients with the inherited variant. A minority of patient with bilateral… (More)
National Institutes of Health

Papers overview

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2012
2012
The etiology of retinoblastoma remains poorly understood. In the present study, we examined associations between perinatal… (More)
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Review
1999
Review
1999
Mutations in both alleles of the RB1 gene are causal for the development of retinoblastoma, a childhood tumor of the eye. The… (More)
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1997
1997
In most patients with isolated unilateral retinoblastoma, tumor development is initiated by somatic inactivation of both alleles… (More)
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1991
1991
DNA samples from 92 unrelated patients with bilateral retinoblastoma were analyzed by Southern blot hybridization with cDNA and… (More)
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Highly Cited
1987
Highly Cited
1987
The retinoblastoma (Rb) gene is the prototype for a class of recessive human cancer genes in which loss of activity of both… (More)
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Highly Cited
1987
Highly Cited
1987
Retinoblastoma, when it kills by metastasis, almost always does so within 5 years of enucleation. The median time to death was 6… (More)
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1983
1983
Leiomyosarcoma rarely occurs in the orbit and is seldom encountered as a postirradiation sarcoma in any anatomic location. Three… (More)
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1982
1982
In 11 patients, bilateral retinoblastoma presented at a mean age of 6 months and pineoblastoma at 4 years. We suggest that the… (More)
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1981
1981
Thirty-seven patients with bilateral retinoblastoma, groups I, II, and III, were treated with simultaneous bilateral radiation… (More)
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1976
1976
Unilateral retinoblastoma (Rb) is usually a sporadic occurrence while bilateral (multifocal) cases are often familial. Sporadic… (More)
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