FAQ

beta-pyrazolylalanine synthase activity

Known as: beta-(1-pyrazolyl)alanine synthase activity, 3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity, O3-acetyl-L-serine acetate-lyase (adding pyrazole) 
Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+). [EC:2.5.1.51, RHEA:13120]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
012320032018

Papers overview

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2017
2017
Design, synthesis, and evaluation of pyrazolo-pyrazole derivatives on Methylisocitratelyase of Pseudomonas aeruginosa: in silico and in vitro study.
Pseudomonas aeruginosa is an opportunistic micro-organism causing diseases both in animals and humans. In case of human pathology… (More)
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2016
2016
Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch
The membrane-bound transcription factor ATF6α plays a cytoprotective role in the unfolded protein response (UPR), required for… (More)
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2016
2016
Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities.
A series of novel coumarin pyrazole hybrids of biological interest were synthesized from the hydrazones, carbazones and… (More)
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2015
2015
NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell
Retinoid X receptor α (RXRα) and its N-terminally truncated version tRXRα play important roles in tumorigenesis, while some RXR… (More)
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2011
2011
Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives.
The synthesis and pharmacological analyses of a number of pyrazolo[3,4-b]quinoline and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine… (More)
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2006
2006
Concise synthesis of guanidine-containing heterocycles using the Biginelli reaction.
Two general methods for the synthesis of 2-imino-5-carboxy-3,4-dihydropyrimidines were developed using the three-component… (More)
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2005
2005
Palladium-catalyzed coupling of pyrazole triflates with arylboronic acids.
[reaction: see text] A general protocol for the palladium-mediated Suzuki coupling reaction of pyrazole triflates and aryl… (More)
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2005
2005
Polymorphism in Fe[(p-IC6H4)B(3-Mepz)3]2 (pz = pyrazolyl): impact of supramolecular structure on an iron(II) electronic spin-state crossover.
The new ligands Na[(p-IC6H4)B(3-Rpz)3] (R = H, Me) have been prepared by converting I2C6H4 to IC6H4SiMe3 with Li(t)Bu and SiMe3Cl… (More)
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2004
2004
Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing gamma-glutamylcysteine synthetase in the cytosol.
Glutathione (GSH) is the major low molecular weight thiol in plants with different functions in stress defence and the transport… (More)
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2003
2003
Synthesis of heteroaromatic analogues of (2-aryl-1-cyclopentenyl-1-alkylidene)-(arylmethyloxy)amine COX-2 inhibitors: effects on the inhibitory activity of the replacement of the cyclopentene central…
Several heteroaromatic analogues of (2-aryl-1-cyclopentenyl-1-alkylidene)-(arylmethyloxy)amine COX-2 inhibitors, in which the… (More)
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