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beta-pyrazolylalanine synthase activity

Known as: beta-(1-pyrazolyl)alanine synthase activity, 3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity, O3-acetyl-L-serine acetate-lyase (adding pyrazole) 
Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+). [EC:2.5.1.51, RHEA:13120]
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Intersystem Crossing Pathway in Quinoline-Pyrazole Isomerism: A Time-Dependent Density Functional Theory Study on Excited-State Intramolecular Proton Transfer.
The dynamics of the excited-state intramolecular proton-transfer (ESIPT) reaction of quinoline-pyrazole (QP) isomers, designated… Expand
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Highly Cited
2012
Highly Cited
2012
Regioselective synthesis of pyrazole triflones based on triflyl alkyne cycloadditions.
The regioselective synthesis of pyrazole triflones has been achieved by 1,3-dipolar cycloaddition of triflyl alkynes and… Expand
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2011
2011
Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity.
Tridentate pyrazole-containing ligands of the Schiff base type, SalPz - HL(1), Cl(2)SalPz - HL(2) and I(2)SalPz - HL(3), were… Expand
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Highly Cited
2008
Highly Cited
2008
Synthesis and Antimicrobial Activity of Some New Pyrazole, Fused Pyrazolo[3,4-d]-pyrimidine and Pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine Derivatives
Hydrazonyl bromides 2a,b reacted with active methylene compounds (dibenzoylmethane, acetylacetone, ethyl acetoacetate, phenacyl… Expand
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Highly Cited
2006
Highly Cited
2006
Concise synthesis of guanidine-containing heterocycles using the Biginelli reaction.
Two general methods for the synthesis of 2-imino-5-carboxy-3,4-dihydropyrimidines were developed using the three-component… Expand
Highly Cited
2005
Highly Cited
2005
Chemically Distinct Ligands Promote Differential CB1 Cannabinoid Receptor-Gi Protein Interactions
To understand how structurally distinct ligands regulate CB1 receptor interactions with Gi1, Gi2, and Gi3, we quantified the Gαi… Expand
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Highly Cited
2005
Highly Cited
2005
Polymorphism in Fe[(p-IC6H4)B(3-Mepz)3]2 (pz = pyrazolyl): impact of supramolecular structure on an iron(II) electronic spin-state crossover.
The new ligands Na[(p-IC6H4)B(3-Rpz)3] (R = H, Me) have been prepared by converting I2C6H4 to IC6H4SiMe3 with Li(t)Bu and SiMe3Cl… Expand
2005
2005
Palladium-catalyzed coupling of pyrazole triflates with arylboronic acids.
[reaction: see text] A general protocol for the palladium-mediated Suzuki coupling reaction of pyrazole triflates and aryl… Expand
Highly Cited
2004
Highly Cited
2004
Synthesis of some new annulated pyrazolo-pyrido (or pyrano) pyrimidine, pyrazolopyridine and pyranopyrazole derivatives.
The bifunctional pyrazolopyridine (2) and pyrano-pyrazole (3) derivatives were prepared by the reaction of 2-(2,4-dinitrophenyl… Expand
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1976
1976
Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo(1,5-alpha)pyrimidines.
A series of 3-substituted 5,7-dihydroxypyrazolo[1,5-alpha]pyrimidines containing various aromatic [phenyl- (3e), 3-pyridyl- (3f… Expand
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