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beta-ketoacyl-acyl-carrier-protein synthase III activity

Known as: FabH, 3-oxoacyl:ACP synthase III activity, beta-ketoacyl-acyl carrier protein synthase III activity 
Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2. [EC:2.3.1.180]
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
As a naturally wide distributed flavone, chrysin exhibits numerous biological activities including anticancer, anti-inflammatory… Expand
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Highly Cited
2007
Highly Cited
2007
Emergence of bacterial resistance is a major issue for all classes of antibiotics; therefore, the identification of new classes… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Condensing enzymes are essential in type II fatty acid synthesis and are promising targets for antibacterial drug… Expand
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2003
2003
beta-Ketoacyl-acyl carrier protein (ACP) synthase III (KAS III, also called acetoacetyl-ACP synthase) encoded by the fabH gene is… Expand
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Highly Cited
2000
Highly Cited
2000
A universal set of genes encodes the components of the dissociated, type II, fatty acid synthase system that is responsible for… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND beta-Ketoacyl-acyl carrier protein synthase III (FabH) initiates elongation in type II fatty acid synthase systems… Expand
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Highly Cited
1998
Highly Cited
1998
A vestigial, nonphotosynthetic plastid has been identified recently in protozoan parasites of the phylum Apicomplexa. The… Expand
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Highly Cited
1996
Highly Cited
1996
  • R. Heath, C. Rock
  • The Journal of Biological Chemistry
  • 1996
  • Corpus ID: 24109052
β-Ketoacyl-acyl carrier protein (ACP) synthase III (the fabH gene product) condenses acetyl-CoA with malonyl-ACP to initiate… Expand
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Highly Cited
1996
Highly Cited
1996
  • R. Heath, C. Rock
  • The Journal of Biological Chemistry
  • 1996
  • Corpus ID: 46163144
Long chain acyl-acyl carrier protein (acyl-ACP) has been implicated as a physiological inhibitor of fatty acid biosynthesis since… Expand
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Highly Cited
1992
Highly Cited
1992
beta-Ketoacyl-acyl carrier protein (ACP) synthase III catalyzes the condensation of acetyl-CoA with malonyl-ACP in dissociated… Expand
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