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beta-arrestin 2

Known as: beta-Arrestin 2 [Chemical/Ingredient], ARRB2 Protein, beta Arrestin 2 
A beta-arrestin that functions similarly to BETA-ARRESTIN 1 in regulating signaling by G-PROTEIN-COUPLED RECEPTORS. It is expressed at high levels in… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Arrestins interact with G-protein-coupled receptors (GPCRs) to block interaction with G proteins and initiate G-protein… Expand
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Highly Cited
2011
Highly Cited
2011
Arrestins are multi-functional proteins that regulate signaling and trafficking of the majority of G protein-coupled receptors… Expand
Review
2010
Review
2010
Seven-transmembrane receptors (7TMRs; also known as G protein-coupled receptors) are the largest class of receptors in the human… Expand
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Highly Cited
2010
Highly Cited
2010
We have compared the ability of a number of μ-opioid receptor (MOPr) ligands to activate G proteins with their abilities to… Expand
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Highly Cited
2005
Highly Cited
2005
Morphine activates μ-opioid receptors (MORs) without promoting their rapid endocytosis in a number of cell types. A previous… Expand
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Highly Cited
2004
Highly Cited
2004
Previous studies have demonstrated that the interaction of the angiotensin II type 1A receptor (AT1AR) carboxyl-terminal tail… Expand
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Highly Cited
2002
Highly Cited
2002
The non-visual arrestins, arrestin-2 and arrestin-3, play a critical role in regulating the signaling and trafficking of many G… Expand
Highly Cited
1999
Highly Cited
1999
We investigated the role of arrestins in the trafficking of human α2-adrenergic receptors (α2-ARs) and the effect of receptor… Expand
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Highly Cited
1996
Highly Cited
1996
THE ability of a system to regulate its responsiveness in the presence of a continuous stimulus, often termed desensitization… Expand
Highly Cited
1996
Highly Cited
1996
The ability of a system to regulate its responsiveness in the presence of a continuous stimulus, often termed desensitization… Expand