beta-adrenergic receptor kinase inhibitory peptide

Known as: betaARK1 inhibitor, betaARKct peptide, beta-adrenergic receptor kinase inhibitor 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

PeptidesRecombinant Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure.
BACKGROUND The upregulation of G protein-coupled receptor kinase 2 in failing myocardium appears to contribute to dysfunctional… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Identification of Nogo as a novel indicator of heart failure.
Numerous genetically engineered animal models of heart failure (HF) exhibit multiple characteristics of human HF, including… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
2007
2007
Endothelial beta2 adrenergic signaling to AKT: role of Gi and SRC.
We have recently demonstrated that endothelial beta(2) adrenergic receptors (beta(2)AR) regulate eNOS activity and consequently… (More)
Is this relevant?
2004
2004
Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts.
BACKGROUND Failing human myocardium is characterized by an attenuated contractile response to beta-adrenergic receptor (betaAR… (More)
Is this relevant?
2004
2004
Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes.
In the heart, insulin-like growth factor-1 (IGF-1) is a pro-hypertrophic and anti-apoptotic peptide. In cultured rat… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
2003
2003
Differential myocardial gene expression in the development and rescue of murine heart failure.
Numerous murine models of heart failure (HF) have been described, many of which develop progressive deterioration of cardiac… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase.
A large number of studies have demonstrated co-purification or co-immunoprecipitation of receptors with G proteins. We have begun… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase.
Recent evidence suggests that many signaling molecules localize in microdomains of the plasma membrane, particularly caveolae. In… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure.
Chronic human heart failure is characterized by abnormalities in beta-adrenergic receptor (betaAR) signaling, including increased… (More)
Is this relevant?
2000
2000
Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction.
When the heart fails, there is often a constellation of biochemical alterations of the beta-adrenergic receptor (betaAR… (More)
Is this relevant?