beta-2'-deoxythioguanosine

Known as: 9H-purine-6-thiol, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl) monohydrate, Beta Thioguanine Deoxyriboside, B-TGDR 
A thiopurine nucleoside derivative with antineoplastic activity. After conversion to the triphosphate, beta-thioguanine deoxyriboside is incorporated… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Thiopurine methyltransferase (TPMT) activity exhibits monogenic co-dominant inheritance, with ethnic differences in the frequency… (More)
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Highly Cited
2000
Highly Cited
2000
Sphingosine-1-phosphate (SPP) has diverse biological functions acting inside cells as a second messenger to regulate… (More)
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Highly Cited
2000
Highly Cited
2000
This study investigated the effects of antidepressant treatment on platelet activation in depressed patients with ischemic heart… (More)
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Highly Cited
1999
Highly Cited
1999
The search for potential targets for ceramide action led to the identification of ceramide-activated protein phosphatases, which… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND PURPOSE Markers of thrombin generation and platelet activation are often elevated in patients with nonvalvular… (More)
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Highly Cited
1996
Highly Cited
1996
The aim of the present study was to determine if the human erythroid (E) and megakaryocytic (MK) lineages were closely linked to… (More)
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Review
1996
Review
1996
Thiopurine S-methyltransferase (TPMT) catalyses the S-methylation of thiopurines such as mercaptopurine and thioguanine. TPMT… (More)
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Highly Cited
1993
Highly Cited
1993
Ceramide is emerging as a putative second messenger mediating effects of extracellular agents on cell growth and differentiation… (More)
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Highly Cited
1990
Highly Cited
1990
ERYTHROMYCIN A, a clinically important polyketide antibiotic, is produced by the Gram-positive bacterium Saccharopolyspora… (More)
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Highly Cited
1988
Highly Cited
1988
Using a clonal culture system, we investigated the hemopoietic effects of purified recombinant IL-5 obtained from conditioned… (More)
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