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benzovesamicol

National Institutes of Health

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Piperidines

Papers overview

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2017
2017
Direct access to the optically active VAChT inhibitor vesamicol and its analogues via the asymmetric aminolysis of meso-epoxides with secondary aliphatic amines.
First highly enantioselective synthesis of biologically important vesamicol, benzovesamicol, and their derivatives was achieved… 
2013
2013
Synthesis and biodistribution of both (±)-5-( 18 F)-fluoroethoxy and (±)-5-( 18 F)-fluoro- propoxy piperazine analogs of benzovesamicol as vesicular acetylcholine transporter ligands (VAChT)
The radiosynthesis and preliminary biological evaluation in rats' brain of two novel piperazine analogs of benzovesamicol as… 
2011
2011
Synthesis and characterization of novel benzovesamicol analogs
Three new racemic vesamicol analogs were successfully prepared in good yields and high purity. All compounds were characterized… 
2011
2011
Powder X-ray study of racemic (2RS,3RS)-5-amino-3-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol.
The title compound, C(20)H(25)N(3)O, an important precursor for the preparation of benzovesamicol analogues for the diagnosis of… 
2010
2010
3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT).
2010
2010
2,2,2-Trifluoro-N-(1a,2,7,7a-tetrahydronaphtho[2,3-b]oxiren-3-yl)acetamide by X-ray powder diffraction.
The title compound, C(12)H(10)F(3)NO(2), an important precursor in the preparation of benzovesamicol analogues for the diagnosis… 
2007
2007
(E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter.
2005
2005
Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter.
1994
1994
Synthesis and in vivo evaluation of a 99m/99Tc-DADT-benzovesamicol: a potential marker for cholinergic neurons.
1994
1994
Direct optical resolution of vesamicol and a series of benzovesamicol analogues by high-performance liquid chromatography.
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