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benzo(a)pyrene-3,6-quinone

Known as: benzo(a)pyrene-3,6-dione 
 
National Institutes of Health

Papers overview

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2001
2001
The intestinal bioavailability and biotransformation of 3-hydroxybenzo(a)pyrene, a major metabolite of benzo(a)pyrene in many… Expand
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Highly Cited
2000
Highly Cited
2000
NQO1-/- mice, along with Chinese hamster ovary (CHO) cells, were used to determine the in vivo role of NAD(P)H:quinone… Expand
Highly Cited
1998
Highly Cited
1998
The role of microsomal NADPH:cytochrome P450 reductase (P450 reductase) and cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1 or… Expand
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Highly Cited
1998
Highly Cited
1998
Benzo(a)pyrene and benzene are human carcinogens. The metabolic activation of these compounds into ultimate mutagenic and… Expand
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Review
1990
Review
1990
1. Isozymes of the cytochromes P-450, UDP-glucuronosyl transferases (UDPGT) and glutathione S-transferases appear to be… Expand
1985
1985
The cytotoxicity of menadione (2-methyl-1,4-naphthoquinone) and benzo(a)pyrene-3,6-quinone (BP-3,6-Q) was tested in cultures of… Expand
1985
1985
Cytotoxic effects of quinones are thought to be mediated by redox cycles between quinones and quinols whereby reactive oxygen… Expand
1983
1983
The roles of two species of cytochrome P-450, the major cytochrome P-450 components of liver microsomes of phenobarbital-treated… Expand
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Highly Cited
1978
Highly Cited
1978
Abstract Benzo( a )pyrene (BP) quinones and 3-OH-BP are the metabolites preferentially converted to glucuronyl conjugates when BP… Expand
1978
1978
Abstract Analysis of repetitive scan difference spectra of incubation mixtures containing liver microsomes from phenobarbital… Expand