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benzene metabolic process
Known as:
benzene metabolism
The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the…
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National Institutes of Health
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Review
2012
Review
2012
Leukemia and Benzene
R. Snyder
International Journal of Environmental Research…
2012
Corpus ID: 5090902
Excessive exposure to benzene has been known for more than a century to damage the bone marrow resulting in decreases in the…
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Highly Cited
2012
Highly Cited
2012
Anaerobic Benzene Oxidation by Geobacter Species
Tian Zhang
,
Timothy S. Bain
,
K. Nevin
,
Melissa A. Barlett
,
D. Lovley
Applied and Environmental Microbiology
2012
Corpus ID: 3248104
ABSTRACT The abundance of Geobacter species in contaminated aquifers in which benzene is anaerobically degraded has led to the…
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Highly Cited
2008
Highly Cited
2008
QM/MM modeling of benzene hydroxylation in human cytochrome P450 2C9.
Christine M. Bathelt
,
A. Mulholland
,
J. Harvey
Journal of Physical Chemistry A
2008
Corpus ID: 207608231
The mechanism of benzene hydroxylation was investigated in the realistic enzyme environment of the human CYP 2C9 by using quantum…
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Highly Cited
1990
Highly Cited
1990
Monoclonal antibody-directed characterization of benzene, ethoxyresorufin and pentoxyresorufin metabolism in rat liver microsomes.
T. Nakajima
,
E. Elovaara
,
S. S. Park
,
H. Gelboin
,
E. Hietanen
,
H. Vainio
Biochemical Pharmacology
1990
Corpus ID: 22425317
Highly Cited
1989
Highly Cited
1989
Effect of exposure concentration, exposure rate, and route of administration on metabolism of benzene by F344 rats and B6C3F1 mice.
P. Sabourin
,
W. Bechtold
,
W. Griffith
,
L. Birnbaum
,
G. Lucier
,
R. Henderson
Toxicology and Applied Pharmacology
1989
Corpus ID: 19092335
Highly Cited
1989
Highly Cited
1989
The effect of dose, dose rate, route of administration, and species on tissue and blood levels of benzene metabolites.
R. Henderson
,
P. Sabourin
,
+4 authors
G. Lucier
Environmental Health Perspectives
1989
Corpus ID: 14126499
Studies were completed in F344/N rats and B6C3F1 mice to determine the effect of dose, dose rate, route of administration, and…
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1989
1989
Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver.
T. Nakajima
,
E. Elovaara
,
S. S. Park
,
H. Gelboin
,
E. Hietanen
,
H. Vainio
Carcinogenesis
1989
Corpus ID: 27804382
The contribution of cytochrome P-450 isozymes to benzene metabolism in liver microsomes from fed, fasted, pyrazole…
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Highly Cited
1988
Highly Cited
1988
Benzene metabolism by ethanol-, acetone-, and benzene-inducible cytochrome P-450 (IIE1) in rat and rabbit liver microsomes.
I. Johansson
,
M. Ingelman-Sundberg
Cancer Research
1988
Corpus ID: 11514104
Ethanol is known to exert a synergistic effect on the toxicity of benzene. In the present investigation it was found that benzene…
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Highly Cited
1986
Highly Cited
1986
Formation of muconaldehyde, an open-ring metabolite of benzene, in mouse liver microsomes: an additional pathway for toxic metabolites.
L. Latriano
,
B. Goldstein
,
G. Witz
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 8990415
It has been proposed that a ring-opened form may be responsible for the toxicity of benzene. The present studies demonstrate that…
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Highly Cited
1973
Highly Cited
1973
Benzene metabolism in mouse liver microsomes.
L. Gonasun
,
C. Witmer
,
J. Kocsis
,
R. Snyder
Toxicology and Applied Pharmacology
1973
Corpus ID: 42063321
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