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bendazac

Known as: 1-benzylindazole-3-oxyacetic acid, bendazolic acid, bindazac 
 
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Drug-induced liver injury (DILI) is a significant consideration for drug development. Current preclinical DILI assessment relying… Expand
2010
2010
Novel bendazac analogues and their salts have been designed and prepared. The resulting compounds (13c-d, 15c, 17c) showed very… Expand
1995
1995
Oxidative damage to lens components is associated with cataract formation and reactive oxygen species (ROS) overproduction at… Expand
1995
1995
Bendazac has been used as an anti-cataractogenic drug. It has been reported that this acts by preventing protein denaturation. In… Expand
1994
1994
Ocular and systemic absorption of bendazac was investigated after topical administration to rabbits of 0.5% solutions of bendazac… Expand
1990
1990
It is conceivable that drugs with anticataract potential possess antioxidant activity. Using defined chelating agents and… Expand
1988
1988
Glucose-6-phosphate and galactose react non-enzymically with lens proteins. The rates of these reactions are decreased by 5… Expand
1987
1987
The compounds silibin, sorbinil and bendazac act as hydroxyl radical scavengers, when the hydroxyl radical is generated by the… Expand
1986
1986
The reaction of lens proteins with cyanate (carbamylation) causes many changes seen in human cataract including disruption of the… Expand
1983
1983
Bendazac, as such or in the form of its l-lysine salt, has a protective effect against lens protein denaturation both in vitro… Expand