bendazac

Drug-induced liver injury (DILI) is a significant consideration for drug development. Current preclinical DILI assessment relying… (More)

Bendazac has been used as an anti-cataractogenic drug. It has been reported that this acts by preventing protein denaturation. In… (More)

Ocular and systemic absorption of bendazac was investigated after topical administration to rabbits of 0.5% solutions of bendazac… (More)

It is conceivable that drugs with anticataract potential possess antioxidant activity. Using defined chelating agents and… (More)

Enhanced non-enzymic glycation of proteins has been suggested to play a role in the pathogenesis of diabetic microangiopathy… (More)

Glucose-6-phosphate and galactose react non-enzymically with lens proteins. The rates of these reactions are decreased by 5… (More)

The compounds silibin, sorbinil and bendazac act as hydroxyl radical scavengers, when the hydroxyl radical is generated by the… (More)

The pharmacokinetics of bendazac and its major metabolite, 5-hydroxybendazac, have been investigated in 15 patients with moderate… (More)

The plasma levels of the lysine salt of bendazac were studied in man after repeated administrations. The substance was… (More)

Bendazac, as such or in the form of its l-lysine salt, has a protective effect against lens protein denaturation both in vitro… (More)