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beclobrinic acid
Known as:
2-(4 ((4-chlorophenyl)methyl)phenoxy)-2-methyl butanoic acid
, beclobric acid
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Clofibrate
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Effects of clofibric and beclobric acid in rat and monkey hepatocyte primary culture: influence on peroxisomal and mitochondrial β-oxidation and the activity of catalase, glutathione S-transferase…
W. Mennes
,
H. Wortelboer
,
+5 authors
B. Blaauboer
Archives of Toxicology
2009
Corpus ID: 36164192
The effect of hypolipidaemic compounds on peroxisomal fatty acid β-oxidation and on peroxisome morphology in the liver differs…
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1993
1993
In vitro and in vivo irreversible plasma protein binding of beclobric acid enantiomers.
S. Mayer
,
E. Mutschler
,
L. Benet
,
H. Sphahn-Langguth
Chirality
1993
Corpus ID: 22406797
Acyl glucuronides are known to be labile conjugates, which undergo hydrolysis and bind irreversibly to proteins. The lipid…
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1993
1993
Pharmacokinetics of beclobric acid enantiomers and their conjugates after single and multiple oral dosage of racemic beclobrate.
S. Mayer
,
H. Spahn‐Langguth
,
I. Gikalov
,
E. Mutschler
Arzneimittel-Forschung
1993
Corpus ID: 29200307
The chiral lipid regulating agent beclobrate (CAS 55937-99-0), which was marketed as racemate, is - like clofibrate - rapidly…
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1991
1991
Pharmacokinetic studies with the lipid-regulating agent beclobrate: enantiospecific assay for beclobric acid using a new fluorescent chiral coupling component (S-FLOPA).
S. Mayer
,
E. Mutschler
,
H. Spahn‐Langguth
Chirality
1991
Corpus ID: 8259008
The major biotransformation pathway for the chiral lipid-regulating agent beclobrate is conversion to the corresponding…
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Highly Cited
1990
Highly Cited
1990
The effect of beclobric acid and clofibric acid on peroxisomal beta-oxidation and peroxisome proliferation in primary cultures of rat, monkey and human hepatocytes.
B. Blaauboer
,
C. W. van Holsteijn
,
+7 authors
B. Schmid
Biochemical Pharmacology
1990
Corpus ID: 22254812
1990
1990
Effective hypolipidaemic therapy with beclobrate in haemodialysis patients: interference with L-carnitine.
C. Wanner
,
H. Wieland
,
M. Nauck
,
G. Schaeffer
,
P. Schollmeyer
,
W. Hörl
Nephrology, Dialysis and Transplantation
1990
Corpus ID: 22100638
The lipid-reducing effects of a new fibric acid derivative (beclobrate, 100 mg/day), L-carnitine (15 mg/ kg b.w. thrice weekly i…
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1987
1987
Induction of peroxisomal fatty acyl-CoA oxidase and microsomal laurate hydroxylase activities by beclobric acid and two metabolites in primary cultures of rat hepatocytes.
T. Kocarek
,
D. Feller
Biochemical Pharmacology
1987
Corpus ID: 32785377
1987
1987
[Pharmacokinetics and bioequivalence of two peroral beclobrate preparations].
I. Gikalov
,
U. Ifflaender
Arzneimittel-Forschung
1987
Corpus ID: 46708776
The pharmacokinetics of beclobrate (ethyl(+/-)-2-[[alpha-(p-chlorophenyl)-p-tolyl]-oxy]-2-methylbutyrate, SGD 24774), a new lipid…
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1985
1985
[Metabolism of beclobrate in rat and man].
V. Roth
,
A. Prox
,
U. Ifflaender
Arzneimittel-Forschung
1985
Corpus ID: 34028321
The major pathway of biotransformation of beclobrate [(2-[4-[(4-chlorophenyl)methyl]phenoxy]-2-methylbutyric acid ethyl ester] is…
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1985
1985
Beclobrinic acid--a new hypolipidemic agent--inhibits in vitro human platelet activation by blocking prostaglandin synthesis.
K. Anwer
,
J. Gabis
,
K. Romstedt
,
C. Gojer
,
Huzoor-Akbar
Life Science
1985
Corpus ID: 36626227
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