batracylin

Known as: 8-Aminoisoindolo(1,2-b)quinazolin-12(10H)-one, 8-aminoisoindolo(1,2-b)quinazolin-12(10H)one, Daniquidone 
A water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2016
012319882016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Batracylin (NSC-320846) is a dual inhibitor of DNA topoisomerases I and II. Batracylin advanced as an anticancer agent to Phase I… (More)
Is this relevant?
2007
2007
Batracylin (8-aminoisoindolo [1,2-b]quinazolin-10(12H)-one; NSC320846) is an investigational clinical anticancer agent. Previous… (More)
Is this relevant?
2003
2003
The synthesis of MDP (muramyl dipeptide) or nor-MDP (normuramyl dipeptide) conjugates modified at the peptide part with… (More)
Is this relevant?
1999
1999
Batracylin (8-aminoisoindolo[1,2-b]quinazolin-12(10 H)-one; BAT) is a heterocyclic amine that exhibits antitumor activity in a… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
1996
1996
The role of acetylation in the genotoxicity of the heterocyclic amine, batracylin, was evaluated in Salmonella typhimurium… (More)
Is this relevant?
1994
1994
Batracylin (8-aminoisoindolo[1,2-b]quinazolin-12(10H)-one), an experimental chemotherapeutic agent, is a heterocyclic aryl amine… (More)
Is this relevant?
1991
1991
Batracylin (NSC-320846) is a quinalzolineone recently evaluated as a potential antitumor agent by the National Cancer Institute… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1989
1989
Batracylin (NSC 320846) is a water insoluble, solid tumor active compound discovered by the Developmental Therapeutics Program of… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
1988
1988
Batracylin (NSC 320846, BAY H 2049), given ip on days 2 and 9 at a dose of 400 mg/kg, inhibited tumor growth completely in 80–100… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
1988
1988
The antitumour efficacy of batracylin was investigated in vivo against murine tumours. The drug displayed an original spectrum of… (More)
Is this relevant?