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basimglurant

National Institutes of Health

Papers overview

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Review
2017
Review
2017
Clinical and preclinical studies suggest that dysfunction of the glutamatergic system is implicated in mood disorders such as… 
2017
2017
Abstract 1. The emerging technique of employing intravenous microdose administration of an isotope tracer concomitantly with an… 
2017
2017
Basimglurant, a novel mGlu5-negative allosteric modulator under development for the treatment of major depressive disorder, is… 
Highly Cited
2016
Highly Cited
2016
IMPORTANCE Antagonism of the postsynaptic metabotropic glutamate subtype 5 receptor is a novel approach to modulate glutamatergic… 
Review
2016
Review
2016
Chronic stress-related psychiatric conditions such as anxiety, depression, and alcohol abuse are an enormous public health… 
Highly Cited
2015
Highly Cited
2015
Major depressive disorder (MDD) is a serious public health burden and a leading cause of disability. Its pharmacotherapy is… 
Highly Cited
2015
Highly Cited
2015
Negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGlu5) have potential for the treatment of… 
2015
2015
Introduction: Metabotropic glutamate receptor 5 (mGlu5) negative allosteric modulators (NAM) such as 2-Methyl-6-(phenylethynyl…