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aziridinomitosene

 
National Institutes of Health

Papers overview

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2011
2011
Anionic aromatic ipso-substitution has allowed an aziridine ring to be fused onto pyrrolo[1,2-a]benzimidazole. This diazole… Expand
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2009
2009
The clinically used antitumor antibiotic mitomycin C requires a reductive activation to be converted to a bis-electrophile that… Expand
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2007
2007
Highly substituted, tethered alkyne dipolarophiles participate in the internal 2 + 3 cycloaddition with azomethine ylides… Expand
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2007
2007
Hindered N-silylamines were examined for their utility to serve as protecting groups for the labile aziridine nitrogen found… Expand
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2005
2005
The aziridinomitosene derivative (1S,2S)-6-desmethyl(methylaziridino)mitosene (4) was shown to alkylate plasmid DNA at pH 7.4 in… Expand
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2004
2004
The bicyclic pyrrole ketone 16 has been prepared by using an oxaza-Claisen rearrangement, followed by nitrogen deprotection… Expand
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2004
2004
A convergent synthetic route to the 1,2-aziridinopyrrolo(1,2-a)indole 34 has been developed. Key features of this route include… Expand
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2002
2002
Treatment of 11a with methyllithium affords the destannylated product 12 together with a small amount of tetracyclic product… Expand
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2000
2000
Intermolecular alkylation of the aziridinyl oxazole 20 using PhSO(2)CH(2)CH(2)OTf is possible despite the presence of potentially… Expand
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1996
1996
 
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