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Azinomycin B is a potent antitumor antibiotic that features a set of unusual, densely assembled functionalities. Among them, the… Expand Azinomycin B is a complex natural product containing densely assembled functionalities with potent antitumor activity. Cloning… Expand Azinomycin B is an environmental DNA crosslinking agent produced by the soil microorganism Streptomyces sahachiroi. While the… Expand Studies on the mechanism of action of the antitumor agent azinomycin B in vitro suggest that the drug elicits its lethal effects… Expand 13C-labelled acetate efficiently labels the antitumour natural product azinomycin B, revealing a polyketide origin for the… Expand Evaluation of the sequence selectivity, noncovalent association, and orientation of the DNA cross-linking agent azinomycin B on… Expand A new set of charges specifically developed for biologically relevant N7-alkylated purine adducts have been implemented in the… Expand Azinomycin B (also known as carzinophilin A) contains two electrophilic functional groups-an epoxide and an aziridine residue… Expand A computational model for the covalent interstrand DNA cross-linking of the antitumor agent azinomycin B is reported and is based… Expand Azinomycins A and B, isolated from the culture broth of Streptomyces griseofuscus S 42227, were examined for antitumor activities… Expand