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avagacestat
Known as:
(2R)-2-(N-((4-Chlorophenyl)sulfonyl)-N-((2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl)methyl)amino)-5,5,5-trifluoropentanamide
, Pentanamide, 2-(((4-chlorophenyl)sulfonyl)((2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl)methyl)amino)-5,5,5-trifluoro-, (2R)-
National Institutes of Health
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BMS 708163
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2013
2013
Has inhibition of Aβ production adequately been tested as therapeutic approach in mild AD? A model-based meta-analysis of γ-secretase inhibitor data
Camilla Niva
,
J. Parkinson
,
Fredrik Olsson
,
E. van Schaick
,
J. Lundkvist
,
S. Visser
European Journal of Clinical Pharmacology
2013
Corpus ID: 253782291
To date, γ-secretase inhibition is the most frequently studied mechanism of reducing Aβ in clinical trials with as yet no…
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