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autologous immunoglobulin idiotype-KLH conjugate vaccine

Known as: recombinant Id-KLH, Autologous Immunoglobulin Idiotype-Keyhole Limpet Hemocyanin Conjugate Vaccine, Id-KLH conjugate vaccine 
A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual's tumor cells which are conjugated to keyhole limpet… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
PURPOSE This double-blind, randomized, phase III clinical trial evaluated time to progression (TTP) and overall survival in women… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE Melanomas, sarcomas, and neuroblastomas abundantly express the ganglioside GD2 on the cell surface where it is… Expand
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Highly Cited
2002
Highly Cited
2002
Tumor-specific clonal immunoglobulin expressed by B-cell lymphomas (idiotype [Id]) can serve as a target for active immunotherapy… Expand
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Highly Cited
2002
Highly Cited
2002
Abstract The aim of this study was to test the hypothesis that both growth differential factor 9 (GDF9) and bone morphogenetic… Expand
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Review
2001
Review
2001
In the year 2000, an estimated 1220 100 new cases of invasive cancer will be diagnosed in the United States, and about 552 200… Expand
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Highly Cited
2000
Highly Cited
2000
The unique Ag-presenting capabilities of dendritic cells (DCs) make them attractive vehicles for the delivery of therapeutic… Expand
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Highly Cited
2000
Highly Cited
2000
The idiotype (Id) determinants on the multiple myeloma immunoglobulin can serve as tumor-specific antigens. An anti-Id immune… Expand
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Highly Cited
1997
Highly Cited
1997
Gene-targeted mice deficient for IL-2 (IL-2 -/- mice) are free of apparent disease when maintained under germfree conditions but… Expand
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Highly Cited
1989
Highly Cited
1989
A single intracheal dose of liposome-encapsuled dichloro-methylene-diphosphonate resulted in the elimination of alveolar… Expand
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Highly Cited
1969
Highly Cited
1969
Summary A technique was developed for the detection of individual cells producing anti-TNP antibody by the hemolytic plaque… Expand
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