autologous immunoglobulin idiotype-KLH conjugate vaccine

Known as: recombinant Id-KLH, Autologous Immunoglobulin Idiotype-Keyhole Limpet Hemocyanin Conjugate Vaccine, Id-KLH conjugate vaccine 
A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual's tumor cells which are conjugated to keyhole limpet… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2015
01219832015

Papers overview

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2015
2015
We report the first evaluation of plant-made conjugate vaccines for targeted treatment of B-cell follicular lymphoma (FL) in a… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE Vaccination with hybridoma-derived autologous tumor immunoglobulin (Ig) idiotype (Id) conjugated to keyhole limpet… (More)
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2009
2009
PURPOSE To evaluate patient-specific immunotherapy with mitumprotimut-T (idiotype keyhole limpet hemocyanin [Id-KLH]) and… (More)
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2008
2008
Therapeutic vaccination of B cell lymphoma patients with tumor-specific Ig (idiotype, or Id) chemically coupled to the… (More)
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2007
2007
Idiotype protein (Id) secreted by myeloma cells is the best-characterized tumor-specific antigen and is widely used in clinical… (More)
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2006
2006
BACKGROUND AND OBJECTIVE To combine the use of idiotype-pulsed allogeneic dendritic cells (alloDC) and soluble protein Id… (More)
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Highly Cited
2002
Highly Cited
2002
Tumor-specific clonal immunoglobulin expressed by B-cell lymphomas (idiotype [Id]) can serve as a target for active immunotherapy… (More)
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2000
2000
The unique Ag-presenting capabilities of dendritic cells (DCs) make them attractive vehicles for the delivery of therapeutic… (More)
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2000
2000
The idiotype (Id) determinants on the multiple myeloma immunoglobulin can serve as tumor-specific antigens. An anti-Id immune… (More)
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Highly Cited
1996
Highly Cited
1996
The idiotype of the Ig expressed by a B-cell malignancy (Id) can serve as a unique tumor-specific antigen and as a model for… (More)
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