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autologous immunoglobulin idiotype-KLH conjugate vaccine

Known as: recombinant Id-KLH, Autologous Immunoglobulin Idiotype-Keyhole Limpet Hemocyanin Conjugate Vaccine, Id-KLH conjugate vaccine 
A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual's tumor cells which are conjugated to keyhole limpet… 
National Institutes of Health

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NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Macrophages induce an allergen-specific and long-term suppression in a mouse asthma model
Increasing evidence suggests that macrophages (Mφ) play a crucial downregulatory role in the initiation and progression of… 
1998
1998
A novel and efficient method for synthetic carbohydrate conjugate vaccine preparation: synthesis of sialyl Tn-KLH conjugate using a 4-(4-N-maleimidomethyl) cyclohexane-1-carboxyl hydrazide (MMCCH…
STn (NeuAcα2→6GalNAcα-O-Ser/Thr) is a carbohydrate epitope overexpressed in various human carcinomas. Clinical trials are… 
Highly Cited
1997
Highly Cited
1997
Induction and prevention of colonic inflammation in IL-2-deficient mice.
Gene-targeted mice deficient for IL-2 (IL-2 -/- mice) are free of apparent disease when maintained under germfree conditions but… 
Highly Cited
1996
Highly Cited
1996
Active immunization against vasoactive intestinal peptide prevents photo-induced prolactin secretion in turkeys.
Photostimulation initiates and maintains the rise in circulating prolactin (PRL) observed during the reproductive cycle of the… 
Highly Cited
1992
Highly Cited
1992
Generation of B cell memory and affinity maturation. Induction with Th1 and Th2 T cell clones.
We used an adoptive transfer system and CD4+ T cell clones with defined lymphokine profiles to examine the role of CD4+ T cells… 
Highly Cited
1978
Highly Cited
1978
Enhancement of carrier-specific helper T cell function by the synthetic adjuvant, N-acetyl muramyl-L-alanyl-D-isoglutamine (MDP).
The adjuvant effect of a synthetic peptidoglycan, muramyl dipeptide (N-acetyl muramyl-L-alanyl-D-isoglutamine, MDP), was studied… 
Highly Cited
1976
Highly Cited
1976
Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources.
T cell-containing lymphoid populations produce a nonantigen-specific mediator(s) (NSM) which can replace T cell helper function… 
Highly Cited
1976
Highly Cited
1976
Antibody response to phosphorylcholine in vitro. II. Analysis of T‐dependent and T‐independent responses
Spleen cells, from BALB/c mice primed with keyhole limpet hemocyanin (KLH), were stimulated with heat‐killed vaccine of rough… 
Highly Cited
1975
Highly Cited
1975
B Cell heterogeneity - difference in the size of B lymphocytes responding to T dependent and T independent antigens.
Highly Cited
1974
Highly Cited
1974
Direct triggering of B lymphocytes by insolubilized antigen
The in vitro immune response of mouse spleen cells to trinitrophenylated keyhole limpet hemocyanin (TNP‐KLH) conjugated onto… 
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