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asperlicin

Known as: (S-(2alpha,9beta,9(R*),9alpha,beta))-6,7-dihydro-7-((2,3,9,9a-tetrahydro-9-hydroxy-2-(2-methylpropyl)-3-oxo-1H-imidazo(1,2-a)indol-9-yl)methyl)quinazolino(3,2-a)(1,4)benzodiazepine-5,13-dione, Quinazolino(3,2-a)(1,4)benzodiazepine-5,13-dione, 6,7-dihydro-7-((2,3,9,9a-tetrahydro-9-hydroxy-2-(2-methylpropyl)-3-oxo-1H-imidazo(1,2-a)indol-9-yl)methyl)-, (2S-(2alpha,9beta,9(R*),9abeta))- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzodiazepinonesHormone Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Synthesis and evaluation of asperlicin analogues as non-peptidal cholecystokinin-antagonists.
The SAR of Asperlicin analogues is reported, leading to bioactive 1,4-benzodiazepine-2-ones, which were prepared in a 3 step… 
Review
1998
Review
1998
CCK receptor antagonists.
  • J. Dunlop
  • General Pharmacology
  • 1998
  • Corpus ID: 22579558
Highly Cited
1993
Highly Cited
1993
5-N-acetylardeemin, a novel heterocyclic compound which reverses multiple drug resistance in tumor cells. II. Isolation and elucidation of the structure of 5-N-acetylardeemin and two congeners.
A family of novel compounds has been detected and isolated following an assay for the attenuation of multiple drug resistance in… 
1988
1988
On the biosynthesis of asperlicin and the directed biosynthesis of analogs in Aspergillus alliaceus.
Feeding of 14C-labeled amino acids to resting cells of Aspergillus alliaceus strongly supported the intuitive hypothesis that… 
1986
1986
Characterization of [3H]pentagastrin binding in guinea pig gastric glands--an alternative convenient ligand for receptor binding assay.
1986
1986
A new simple mouse model for the in vivo evaluation of cholecystokinin (CCK) antagonists: comparative potencies and durations of action of nonpeptide antagonists.
1986
1986
Cholecystokinin antagonists. Synthesis of asperlicin analogues with improved potency and water solubility.
Seventeen analogues of the selective, competitive cholecystokinin (CCK) antagonist asperlicin 1 were prepared. These compounds… 
Highly Cited
1985
Highly Cited
1985
A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus.
A new, competitive, nonpeptide cholecystokinin (CCK) antagonist, asperlicin, was isolated from the fungus Aspergillus alliaceus… 
Highly Cited
1985
Highly Cited
1985
Asperlicin, a novel non-peptidal cholecystokinin antagonist from Aspergillus alliaceus. Fermentation, isolation and biological properties.
The fermentation and isolation of a new, non-peptide cholecystokinin antagonist, asperlicin, produced by Aspergillus alliaceus is… 
1985
1985
Asperlicin, a novel non-peptidal cholecystokinin antagonist from Aspergillus alliaceus. Structure elucidation.
Asperlicin (1, C31H29N5O4) is a novel cholecystokinin antagonist produced by Aspergillus alliaceus. The structure of asperlicin… 
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