asparaginase activity

Known as: L-asparaginase activity, L-asparagine amidohydrolase activity, alpha-asparaginase activity 
Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3. [EC:3.5.1.1]
National Institutes of Health

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ASPARAGINASEcrasnitin activity

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2017
2017
Extracellular vesicles are independent metabolic units with asparaginase activity
Extracellular vesicles (EVs) are membrane particles involved in the exchange of a broad range of bioactive molecules between… (More)
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Review
2005
Review
2005
Pharmacokinetic/pharmacodynamic relationships of asparaginase formulations: the past, the present and recommendations for the future.
The discovery of the tumour-inhibitory properties of asparaginase began 50 years ago with the observation that guinea-pig serum… (More)
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Highly Cited
2004
Highly Cited
2004
Asparaginase antibody and asparaginase activity in children with higher-risk acute lymphoblastic leukemia: Children's Cancer Group Study CCG-1961.
We investigated the anti-asparaginase antibody (Ab) and asparaginase enzymatic activity in the sera of 1,001 patients (CCG-1961… (More)
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2001
2001
Sequence analysis of enzymes with asparaginase activity.
Asparaginases catalyze the hydrolysis of asparagine to aspartic acid and ammonia. Enzymes with asparaginase activity play an… (More)
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2001
2001
Pharmacokinetics of native Escherichia coli asparaginase (Asparaginase medac) and hypersensitivity reactions in ALL-BFM 95 reinduction treatment.
Repeated asparaginase treatment has been associated with hypersensitivity reactions against the bacterial macromolecule in a… (More)
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Highly Cited
1996
Highly Cited
1996
Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations.
The antileukaemic enzyme L-asparaginase is used to achieve the greatest possible reduction in blood levels of the amino acid… (More)
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1991
1991
l-Asparaginase activity of soils
A simple, precise, and sensitive method to assay l-asparaginase (l-asparagine amidohydrolase, EC 3.5.1.1) activity in soils is… (More)
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1991
1991
Factors affecting l-asparaginase activity in soils
Studies on the distribution of l-asparaginase in soil profile samples revealed that its activity generally decreases with sample… (More)
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1990
1990
Characterization and partial purification of L-asparaginase from Corynebacterium glutamicum.
A high L-asparaginase (L-asparagine amidohydrolase: EC 3.5.1.1) activity was found under conditions of lysine overproduction in… (More)
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Highly Cited
1961
Highly Cited
1961
Evidence that the L-Asparaginase Activity of Guinea Pig Serum is responsible for its Antilymphoma Effects
THE inhibitory action of guinea pig serum on the cells of three transplantable mouse and rat lymphomas in vivo was described some… (More)
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