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asocainol

Known as: (+-)-6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-phenethyl-5H-dibenz(d,f)azonine-1-ol 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Azocines

Papers overview

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1994
1994
Interaction of antiarrhythmic drugs with model membranes.
1993
1993
X-Ray Studies on Phospholipid Bilayers. XIV. Interactions with the Antiarrhytmic Asocainol
Asocainol (ASOC) belongs to class I of the antiarrhytmic drugs, i.e., those that exert their action at the level of the sodium… 
1992
1992
Enantioselectivity of asocainol studied at different conditions: a novel approach to check the feasibility of molecular models of antiarrhythmic drug action
SummaryIn terms of the “guarded receptor” hypothesis, changes in potency of Na+ channel blocking drugs reflect alterations in… 
1990
1990
Molecular Pharmacological Aspects of Antiarrhythmic Activity, II1): Interaction of Class I Compounds with Calmodulin
We have tested the calmodulin (CaM) inhibitory potency of class I antiarrhythmics in the phosphodiesterase (PDE) assay. The… 
1987
1987
Electrophysiologic effects of asocainol, a new antiarrhythmic agent with predominant class I action.
In experiments on 6 mongrel dogs the electrophysiologic effects of the new antiarrhythmic compound (+/-)-6,7,8,9-tetrahydro-2,12… 
1984
1984
Asocainol, a new antiarrhythmic drug with natrium- and calcium-antagonistic effects on ventricular myocardium.
In isolated guinea pig papillary muscles, asocainol, a new antiarrhythmic drug, and its optical isomers exert a concentration… 
1984
1984
Racemic asocainol, process for its production, and its use in the control of reizleitungsstoerungen
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