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asocainol

Known as: (+-)-6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-phenethyl-5H-dibenz(d,f)azonine-1-ol 
 
National Institutes of Health

Papers overview

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2004
2004
SummaryThe studies deal with electrophysiological effects of asocainol [(±)-6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-phenetyl… Expand
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2004
2004
SummaryIn terms of the “guarded receptor” hypothesis, changes in potency of Na+ channel blocking drugs reflect alterations in… Expand
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1995
1995
Several hypotheses suggest that the molecular mechanism of action of class I antiarrhythmic drugs (AAD) involve non-specific… Expand
1994
1994
Several hypotheses link the molecular mechanism of action of the antiarrhythmic drugs (AAD) that belong to class I to nonspecific… Expand
1993
1993
Asocainol (ASOC) belongs to class I of the antiarrhytmic drugs, i.e., those that exert their action at the level of the sodium… Expand
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1990
1990
The effect of nineteen antiarrhythmic agents on nonenzymatic lipid peroxidation, using rat hepatic microsomes, was studied. Lipid… Expand
1990
1990
We have tested the calmodulin (CaM) inhibitory potency of class I antiarrhythmics in the phosphodiesterase (PDE) assay. The… Expand
1988
1988
Binding of antiarrhythmics to phospholipids has been quantified by measuring the drug-induced fluorescence increase in 8-anilino… Expand
1987
1987
In experiments on 6 mongrel dogs the electrophysiologic effects of the new antiarrhythmic compound (+/-)-6,7,8,9-tetrahydro-2,12… Expand
1984
1984
  • F. Späh
  • Journal of cardiovascular pharmacology
  • 1984
  • Corpus ID: 7640085
In isolated guinea pig papillary muscles, asocainol, a new antiarrhythmic drug, and its optical isomers exert a concentration… Expand