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asocainol

Known as: (+-)-6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-phenethyl-5H-dibenz(d,f)azonine-1-ol 
 
National Institutes of Health

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1995
1995
Several hypotheses suggest that the molecular mechanism of action of class I antiarrhythmic drugs (AAD) involve non-specific… Expand
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1994
1994
Several hypotheses link the molecular mechanism of action of the antiarrhythmic drugs (AAD) that belong to class I to nonspecific… Expand
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1993
1993
Asocainol (ASOC) belongs to class I of the antiarrhytmic drugs, i.e., those that exert their action at the level of the sodium… Expand
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1992
1992
SummaryIn terms of the “guarded receptor” hypothesis, changes in potency of Na+ channel blocking drugs reflect alterations in… Expand
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1990
1990
We have tested the calmodulin (CaM) inhibitory potency of class I antiarrhythmics in the phosphodiesterase (PDE) assay. The… Expand
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1990
1990
The effect of nineteen antiarrhythmic agents on nonenzymatic lipid peroxidation, using rat hepatic microsomes, was studied. Lipid… Expand
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1988
1988
Binding of antiarrhythmics to phospholipids has been quantified by measuring the drug-induced fluorescence increase in 8-anilino… Expand
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1987
1987
In experiments on 6 mongrel dogs the electrophysiologic effects of the new antiarrhythmic compound (+/-)-6,7,8,9-tetrahydro-2,12… Expand
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1984
1984
SummaryThe studies deal with electrophysiological effects of asocainol [(±)-6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-phenetyl… Expand
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1984
1984
  • F. Späh
  • Journal of cardiovascular pharmacology
  • 1984
  • Corpus ID: 7640085
In isolated guinea pig papillary muscles, asocainol, a new antiarrhythmic drug, and its optical isomers exert a concentration… Expand
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