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aromatic-L-amino-acid decarboxylase activity

Known as: aromatic L-amino acid decarboxylase activity, aromatic amino acid decarboxylase activity, aromatic-L-amino-acid carboxy-lyase activity 
Catalysis of the reaction: L-amino acid + H+ = R-H + CO2. [EC:4.1.1.28]
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Alpha‐synuclein is a presynaptic protein strongly implicated in Parkinson's disease (PD). Because dopamine neurons are invariably… Expand
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Highly Cited
1999
Highly Cited
1999
As a potential treatment for Parkinson's disease, viral vector-mediated over-expression of striatal L-aromatic amino acid… Expand
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Highly Cited
1997
Highly Cited
1997
We provide evidence that dopamine receptors differentially modulate tyrosine hydroxylase and aromatic L-amino acid decarboxylase… Expand
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1993
1993
Abstract: Aromatic L‐amino acid decarboxylase (AAAD) activity of mouse striatum and midbrain increased after an intracerebro… Expand
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1986
1986
  • P. Lindström
  • Biochimica et biophysica acta
  • 1986
  • Corpus ID: 45470777
Aromatic-L-amino-acid decarboxylase activity has been measured in intact or homogenised pancreatic islets of ob/ob mice (Umeå ob… Expand
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1982
1982
The enzymatic decarboxylations of l-DOPA and l-5-hydroxytryptophan (l-5-HTP) by aromatic l-amino acid decarboxylase (AADC) were… Expand
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Highly Cited
1981
Highly Cited
1981
Thirty days after castration the concentration of dopamine (DA) was significantly reduced in the septum and n. accumbens septi… Expand
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Highly Cited
1971
Highly Cited
1971
Abstract— The effect of l‐tryptophan loading upon the amount of 5‐HT accumulating in the brains of rats pretreated with a… Expand
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Highly Cited
1971
Highly Cited
1971
Summary We have found a selective reduction in forebrain tryptophan hydroxylase activity afer placement of electrolytic lesions… Expand
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Highly Cited
1969
Highly Cited
1969
Abstract The effects of the four hallucinogenic drugs (phencyclidine, Ditran, LSD-25 and mescaline) upon the metabolism of 5-HT… Expand
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