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arodyn

Known as: acetyl-phenylalanyl-phenylalanyl-phenylalanyl-arginyl-leucyl-arginyl-arginyl-alanyl-arginyl-prolyl-lysinamide, Ac-Phe-Phe-Phe-Arg-Leu-Arg-Arg-Ala-Arg-Pro-Lys-NH2, aromatic dynorphin 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
We are exploring constraining aromatic residues in the kappa opioid receptor selective antagonist arodyn (Ac[Phe1,2,3,Arg4,D-Ala8… Expand
2018
2018
Kappa (κ) opioid receptor selective antagonists are useful pharmacological tools in studying κ opioid receptors and have… Expand
2015
2015
Kappa (κ) opioid receptor (KOR) ligands, particularly antagonists, have received increasing attention due to their therapeutic… Expand
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2011
2011
Peptides containing N‐methylamino acids can exhibit improved pharmacodynamic and pharmacokinetic profiles compared to… Expand
2011
2011
Arodyn (Ac[Phe1,2,3,Arg4,D‐Ala8]Dyn A(1–11)NH2) is an acetylated dynorphin A (Dyn A) analog that is a potent and selective… Expand
2009
2009
Introduction Our laboratory is interested in the design and synthesis of antagonists for kappa opioid receptor (KOP). In addition… Expand
Highly Cited
2007
Highly Cited
2007
Stress contributes to the reinstatement of cocaine-seeking behavior in abstinent subjects. Kappa-opioid receptor antagonists… Expand
2005
2005
We previously reported that the novel dynorphin A (Dyn A, Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln… Expand
2002
2002
Arodyn (aromatic dynorphin) is a novel analogue of the opioid peptide dynorphin A with a nonbasic N-terminus that exhibits… Expand