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arodyn

Known as: acetyl-phenylalanyl-phenylalanyl-phenylalanyl-arginyl-leucyl-arginyl-arginyl-alanyl-arginyl-prolyl-lysinamide, Ac-Phe-Phe-Phe-Arg-Leu-Arg-Arg-Ala-Arg-Pro-Lys-NH2, aromatic dynorphin 
 
National Institutes of Health

Papers overview

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2019
2019
We are exploring constraining aromatic residues in the kappa opioid receptor selective antagonist arodyn (Ac[Phe1,2,3,Arg4,D-Ala8… Expand
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2018
2018
Kappa (κ) opioid receptor selective antagonists are useful pharmacological tools in studying κ opioid receptors and have… Expand
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2015
2015
Kappa (κ) opioid receptor (KOR) ligands, particularly antagonists, have received increasing attention due to their therapeutic… Expand
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2011
2011
Peptides containing N-methylamino acids can exhibit improved pharmacodynamic and pharmacokinetic profiles compared to… Expand
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2011
2011
Arodyn (Ac[Phe¹,²,³,Arg⁴,D-Ala⁸]Dyn A(1-11)NH₂) is an acetylated dynorphin A (Dyn A) analog that is a potent and selective… Expand
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2009
2009
Introduction Our laboratory is interested in the design and synthesis of antagonists for kappa opioid receptor (KOP). In addition… Expand
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Highly Cited
2007
Highly Cited
2007
Stress contributes to the reinstatement of cocaine-seeking behavior in abstinent subjects. Kappa-opioid receptor antagonists… Expand
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2005
2005
We previously reported that the novel dynorphin A (Dyn A, Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln… Expand
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2002
2002
Arodyn (aromatic dynorphin) is a novel analogue of the opioid peptide dynorphin A with a nonbasic N-terminus that exhibits… Expand
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