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aristolochic acid II
Known as:
6-nitrophenanthro(3,4-d)-3-dioxole-5-carboxylic acid
National Institutes of Health
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Aristolochic Acids
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Highly Cited
2010
Highly Cited
2010
DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells
S. Attaluri
,
R. Bonala
,
+6 authors
F. Johnson
Nucleic acids research
2010
Corpus ID: 16099298
Aristolochic acids I and II (AA-I, AA-II) are found in all Aristolochia species. Ingestion of these acids either in the form of…
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Review
2002
Review
2002
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review.
V. Arlt
,
M. Stiborová
,
H. Schmeiser
Mutagenesis
2002
Corpus ID: 42051455
The old herbal drug aristolochic acid (AA), derived from Aristolochia spp., has been associated with the development of a novel…
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Highly Cited
2001
Highly Cited
2001
Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR.
V. Arlt
,
H. Schmeiser
,
G. Pfeifer
Carcinogenesis
2001
Corpus ID: 24155731
The carcinogenic plant extract aristolochic acid (AA) is thought to be the major causative agent in the development of urothelial…
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Highly Cited
1997
Highly Cited
1997
32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy.
C. Bieler
,
M. Stiborová
,
M. Wiessler
,
J. Cosyns
,
C. van Ypersele de Strihou
,
H. Schmeiser
Carcinogenesis
1997
Corpus ID: 29102504
Recently, we reported that aristolochic acid (AA) a naturally occurring nephrotoxin and carcinogen is implicated in a unique type…
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Highly Cited
1994
Highly Cited
1994
Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures.
M. Stiborová
,
R. Fernando
,
H. Schmeiser
,
E. Frei
,
W. Pfau
,
M. Wiessler
Carcinogenesis
1994
Corpus ID: 26035409
We report the analysis of DNA adducts in the target organ (forestomach) of male Sprague-Dawley rats treated orally with two doses…
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Highly Cited
1991
Highly Cited
1991
Activating mutations at codon 61 of the c-Ha-ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice.
H. Schmeiser
,
H. Scherf
,
M. Wiessler
Cancer letters
1991
Corpus ID: 2214659
Highly Cited
1990
Highly Cited
1990
32P-postlabelling analysis of the DNA adducts formed by aristolochic acid I and II.
W. Pfau
,
H. Schmeiser
,
M. Wiessler
Carcinogenesis
1990
Corpus ID: 24122594
We report the quantitation of DNA adducts in target and nontarget organs of male Wistar rats treated orally with five daily doses…
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Highly Cited
1988
Highly Cited
1988
DNA adduct formation of aristolochic acid I and II in vitro and in vivo.
H. Schmeiser
,
K. B. Schoepe
,
M. Wiessler
Carcinogenesis
1988
Corpus ID: 23536891
Aristolochic acid I (AA I) and aristolochic acid II (AA II), the two main ingredients of the carcinogenic plant extract…
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Highly Cited
1987
Highly Cited
1987
Studies on the metabolism of aristolochic acids I and II.
G. Krumbiegel
,
J. Hallensleben
,
W. Mennicke
,
N. Rittmann
,
H. J. Roth
Xenobiotica; the fate of foreign compounds in…
1987
Corpus ID: 21464543
1. After oral administration of aristolochic acid I (AAI) and aristolochic acid II (AAII) to rats, the following metabolites were…
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Highly Cited
1986
Highly Cited
1986
Identification and mutagenicity of metabolites of aristolochic acid formed by rat liver.
H. Schmeiser
,
B. Pool
,
M. Wiessler
Carcinogenesis
1986
Corpus ID: 26516435
The rat liver 9000 g supernatant mediated metabolism of the carcinogenic aristolochic acid, which consists of aristolochic acid I…
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