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arginyl-glycyl-aspartic acid

Known as: RGD Peptide, RGD Cell Adhesion Domain, RGD Tripeptide Sequence 
A consensus tripeptide that is recognized by and for binding to proteins of the integrin family, including many cell adhesion molecules. The one… 
National Institutes of Health

Related topics

Related topics

10 relations
Amino Acid SequenceCalmodulinMADD proteinMFGE8 protein, human

Broader (3)

Antineoplastic AgentsOligopeptidesPeptides

Papers overview

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Highly Cited
2002
Highly Cited
2002
Enhancement of osteogenesis on hydroxyapatite surface coated with synthetic peptide (EEEEEEEPRGDT) in vitro.
Some dental implants are coated with hydroxyapatite (HA), which preferentially binds to bone. Several matrix proteins have an… 
Highly Cited
1991
Highly Cited
1991
Dynamics of leukocyte-platelet adhesion in whole blood
The dynamics of leukocyte-platelet adhesion and platelet-platelet interaction in whole blood are not well understood. Using… 
Highly Cited
1991
Highly Cited
1991
A fibronectin receptor on Candida albicans mediates adherence of the fungus to extracellular matrix.
Binding of fibronectin, an extracellular matrix (ECM) protein, to Candida albicans was measured, and adherence of the fungus to… 
Highly Cited
1990
Highly Cited
1990
Identification of the Arg‐Gly‐Asp sequence in laminin A chain as a latent cell‐binding site being exposed in fragment P1
Highly Cited
1989
Highly Cited
1989
Tenascin mediates cell attachment through an RGD-dependent receptor
Tenascin is an extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during… 
Highly Cited
1989
Highly Cited
1989
Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules.
We investigated that the antimetastatic and antiadhesive activities of peptides based on Arg-Gly-Asp adhesive signal in… 
Highly Cited
1989
Highly Cited
1989
Human melanoma cells express a novel integrin receptor for laminin.
This study sought to determine whether human melanoma cells express integrin-related receptors that mediate their adhesion to… 
Highly Cited
1987
Highly Cited
1987
Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets.
Highly Cited
1987
Highly Cited
1987
The fibronectin cell attachment sequence Arg-Gly-Asp-Ser promotes focal contact formation during early fibroblast attachment and spreading
Cultured fibroblasts form focal contacts (FCs) associated with actin microfilament bundles (MFBs) during attachment and spreading… 
Highly Cited
1985
Highly Cited
1985
Inhibition of fibronectin binding to platelets by proteolytic fragments and synthetic peptides which support fibroblast adhesion.
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