arginase activity

Known as: L-arginase activity, arginine amidinase activity, arginine transamidinase activity 
Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea. [EC:3.5.3.1]

Topic mentions per year

Topic mentions per year

1939-2018
020406019392017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Increases in arginase activity have been reported in a variety of disease conditions characterized by vascular dysfunction… (More)
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Highly Cited
2005
Highly Cited
2005
Myeloid suppressor cells with high arginase activity are found in tumors and spleen of mice with colon and lung cancer. These… (More)
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Highly Cited
2004
Highly Cited
2004
Recent studies suggest that a nitric oxide (NO) deficiency and elevated arginase activity may play a role in the pathogenesis of… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Arginase competes with endothelial nitric oxide synthase (eNOS) for the substrate l-arginine and decreases NO… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although abnormal L-arginine NO signaling contributes to endothelial dysfunction in the aging cardiovascular system… (More)
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Highly Cited
2003
Highly Cited
2003
Asthma is on the rise despite intense, ongoing research underscoring the need for new scientific inquiry. In an effort to provide… (More)
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Highly Cited
1999
Highly Cited
1999
Activated murine macrophages metabolize arginine by two alternative pathways involving the enzymes inducible NO synthase (iNOS… (More)
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Highly Cited
1998
Highly Cited
1998
Activated murine macrophages metabolize L-arginine via two main pathways that are catalyzed by the inducible enzymes nitric oxide… (More)
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Highly Cited
1998
Highly Cited
1998
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to… (More)
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Highly Cited
1994
Highly Cited
1994
We propose a modification of Schimke's method for urea determination as a valuable micromethod for measuring arginase in… (More)
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