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apovincaminic acid

National Institutes of Health

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Broader (1)

Vinca Alkaloids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Pharmacokinetics of vinpocetine and its main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans
SummaryThe pharmacokinetics of vinpocetine (Cavinton®) and of its main metabolite apovincaminic acid (AVA), has been studied in 5… 
2004
2004
Effect of age on the pharmacokinetics of vinpocetine (Cavinton) and apovincaminic acid
SummaryThe pharmacokinetics of vinpocetine and its main metabolite, apovincaminic acid (AVA), were studied in the aged… 
Highly Cited
2004
Highly Cited
2004
Pharmacological and electrographic properties of epileptiform activity induced by elevated K2+ and lowered Ca2+ and Mg2+ concentration in rat hippocampal slices
We studied some of the physiological and pharmacological properties of an in vitro model of epileptic seizures induced by… 
Review
2002
Review
2002
[Neuroprotective effects of vinpocetine in vivo and in vitro. Apovincaminic acid derivatives as potential therapeutic tools in ischemic stroke].
The aim of the present study was to review neuroprotective therapy from the preclinical point of view as a potential tool for the… 
1997
1997
Decrease in cerebral free magnesium concentration following closed head injury and effects of VA-045 in rats.
1993
1993
Synthesis and pharmacological evaluation of (nitrooxy)alkyl apovincaminates.
A series of (nitrooxy)alkyl apovincaminates has been synthesized and evaluated for their effects on vertebral and femoral blood… 
1993
1993
Effect of VA-045 on a closed head injury model in rats.
Highly Cited
1987
Highly Cited
1987
Vinpocetine enhances retrieval of a step-through passive avoidance response in rats
Highly Cited
1986
Highly Cited
1986
Vinpocetine: Nootropic effects on scopolamine-induced and hypoxia-induced retrieval deficits of a step-through passive avoidance response in rats
1984
1984
Cerebral circulatory and cardiac effects of vinpocetine and its metabolite, apovincaminic acid, in anesthetized dogs.
Cerebral circulatory and cardiac actions of vinpocetine and its metabolite, apovincaminic acid (AVA), were studied in… 
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