anthopleurin B

The role of sodium channel closed-state fast inactivation in membrane excitability is not well understood. We compared open- and… Expand

It has been shown recently that polypeptide toxins that modulate the gating properties of voltage-sensitive cation channels are… Expand

Anthopleurin B (ApB) is a type 1 sea anemone toxin, which binds to voltage-sensitive sodium channels (Na(V)'s), thereby delaying… Expand

The polypeptide neurotoxin anthopleurin B (ApB) isolated from the venom of the sea anemone Anthopleura xanthogrammica is one of a… Expand

Anthopleurin B is a potent anemone toxin that binds with nanomolar affinity to the cardiac and neuronal isoforms of the voltage… Expand

Scorpion and sea anemone venoms contain several polypeptides that delay inactivation of voltage-sensitive sodium channels via… Expand

Several polypeptide toxins from sea anemones caused delayed inactivation of mammalian voltage-dependent sodium channels… Expand

Site 3 sea anemone toxins modify inactivation of mammalian voltage-gated Na channels. One variant, anthopleurin A (ApA… Expand

Polypeptide neurotoxins from sea anemones have been useful biological probes for sodium channel function. Cationic residues… Expand

Venom of the sea anemone Anthopleura xanthogrammica contains a minimum of three polypeptide toxins capable of prolonging the… Expand