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anthopleurin B

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2004
01219782004

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1 relation

Broader (1)

Peptides

Related mentions per year

Related mentions per year

1941-2018
19401960198020002020
anthopleurin B
Peptides

Papers overview

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2005
2005
Effects of intravenous magnesium in a prolonged QT interval model of polymorphic ventricular tachycardia focus on transmural ventricular repolarization.
BACKGROUND This study was performed to clarify the antiarrhythmic effects of magnesium sulfate (Mg(++)) in a prolonged QT… (More)
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2004
2004
Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3.
Anthopleurin B (ApB) is a type 1 sea anemone toxin, which binds to voltage-sensitive sodium channels (Na(V)'s), thereby delaying… (More)
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1998
1998
A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B.
The polypeptide neurotoxin anthopleurin B (ApB) isolated from the venom of the sea anemone Anthopleura xanthogrammica is one of a… (More)
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1996
1996
The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B.
Scorpion and sea anemone venoms contain several polypeptides that delay inactivation of voltage-sensitive sodium channels via… (More)
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1996
1996
Importance of highly conserved anionic residues and electrostatic interactions in the activity and structure of the cardiotonic polypeptide anthopleurin B.
Several polypeptide toxins from sea anemones caused delayed inactivation of mammalian voltage-dependent sodium channels… (More)
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1995
1995
Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination.
Site 3 sea anemone toxins modify inactivation of mammalian voltage-gated Na channels. One variant, anthopleurin A (ApA… (More)
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1994
1994
Importance of the unique cationic residues arginine 12 and lysine 49 in the activity of the cardiotonic polypeptide anthopleurin B.
Sea anemone toxins are potentially important tools for understanding the pharmacology of voltage-sensitive sodium channels. We… (More)
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1994
1994
Role of the cationic residues arginine 14 and lysine 48 in the function of the cardiotonic polypeptide anthopleurin B.
Polypeptide neurotoxins from sea anemones have been useful biological probes for sodium channel function. Cationic residues… (More)
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1992
1992
Cloning and expression of wild-type and mutant forms of the cardiotonic polypeptide anthopleurin B.
Venom of the sea anemone Anthopleura xanthogrammica contains a minimum of three polypeptide toxins capable of prolonging the… (More)
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Highly Cited
1988
Highly Cited
1988
QTU prolongation and polymorphic ventricular tachyarrhythmias due to bradycardia-dependent early afterdepolarizations. Afterdepolarizations and ventricular arrhythmias.
Polymorphic ventricular tachyarrhythmias occurred spontaneously during bradycardia in dogs given the inotropic polypeptide… (More)
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