anthopleurin B

The role of sodium channel closed-state fast inactivation in membrane excitability is not well understood. We compared open- and… Expand

It has been shown recently that polypeptide toxins that modulate the gating properties of voltage-sensitive cation channels are… Expand

Anthopleurin B (ApB) is a type 1 sea anemone toxin, which binds to voltage-sensitive sodium channels (Na(V)'s), thereby delaying… Expand

The polypeptide neurotoxin anthopleurin B (ApB) isolated from the venom of the sea anemone Anthopleura xanthogrammica is one of a… Expand

Scorpion and sea anemone venoms contain several polypeptides that delay inactivation of voltage-sensitive sodium channels via… Expand

Several polypeptide toxins from sea anemones caused delayed inactivation of mammalian voltage-dependent sodium channels… Expand

Anthopleurin B is a potent anemone toxin that binds with nanomolar affinity to the cardiac and neuronal isoforms of the voltage… Expand

Site 3 sea anemone toxins modify inactivation of mammalian voltage-gated Na channels. One variant, anthopleurin A (ApA… Expand

Polypeptide neurotoxins from sea anemones have been useful biological probes for sodium channel function. Cationic residues… Expand

Venom of the sea anemone Anthopleura xanthogrammica contains a minimum of three polypeptide toxins capable of prolonging the… Expand