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androsterone dehydrogenase (B-specific) activity

Known as: 3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific), hydroxyprostaglandin dehydrogenase activity, 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity 
Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen… Expand
National Institutes of Health

Papers overview

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2009
2009
The aim of the present study was to investigate pathways of progesterone metabolism in human adipose cells. Adipose tissue… Expand
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Highly Cited
2008
Highly Cited
2008
Aldo-keto reductase (AKR) 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase) regulates ligand access to… Expand
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2006
2006
Androgen-dependent prostate diseases initially require 5alpha-dihydrotestosterone (DHT) for growth. The DHT product 5alpha… Expand
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Highly Cited
2004
Highly Cited
2004
Progesterone plays an essential role in breast development and cancer formation. The local metabolism of progesterone may limit… Expand
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2004
2004
Androgens may improve cognitive performance; however, these effects and mechanisms of androgens are not well understood. Whether… Expand
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Highly Cited
2004
Highly Cited
2004
Androgens may mediate anxiety behaviors; however, these effects and mechanisms of androgens are not well understood. The… Expand
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Review
2001
Review
2001
Allopregnanolone (3alpha,5alpha-TH PROG) and 5alpha-dihydroprogesterone (5alpha-DH PROG), the two most important neuroactive… Expand
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Review
2001
Review
2001
Androgen action in mammals can be regulated at the pre-receptor level by the intracellular formation and degradation of potent… Expand
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Highly Cited
2000
Highly Cited
2000
The kinetic parameters, steroid substrate specificity and identities of reaction products were determined for four homogeneous… Expand
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Highly Cited
1999
Highly Cited
1999
The neurosteroid 3alpha-hydroxysteroid-5alpha-pregnan-20-one (allopregnanolone) acts as a positive allosteric modulator of gamma… Expand
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