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andrographolide

Known as: (1R-(1-alpha(E(S)),4a-beta,5alpha,6alpha,8a-alpha))-3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-2(3H)-furanone, (3E,4S)-4-hydroxy-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidenedecahydronaphthalen-1-yl]ethylidene}dihydrofuran-2(3H)-one, Andrographis 
A labdane diterpenoid that is produced by the Andrographis paniculata plant, which has a broad range of therapeutic applications including anti… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been proven to possess several important… Expand
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Highly Cited
2009
Highly Cited
2009
RATIONALE Persistent activation of nuclear factor (NF)-kappaB has been associated with the development of asthma. Andrographolide… Expand
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Highly Cited
2008
Highly Cited
2008
There has been an enormous interest in the development of alternative medicines for type 2 diabetes, specifically screening for… Expand
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Highly Cited
2004
Highly Cited
2004
NF-κB is a central transcriptional factor and a pleiotropic regulator of many genes involved in immunological responses. During… Expand
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Highly Cited
2003
Highly Cited
2003
Andrographis paniculata plant extract is known to possess a variety of pharmacological activities. Andrographolide, the major… Expand
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Highly Cited
2003
Highly Cited
2003
The antihyperglycemic action of andrographolide, an active principle in the leaves of Andrographis paniculata (Burm. f.) Nees… Expand
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Highly Cited
2002
Highly Cited
2002
We have reported that andrographolide (ANDRO), an active component of Andrographis paniculata, inhibits inflammatory responses by… Expand
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Highly Cited
2000
Highly Cited
2000
A phase I dose‐escalating clinical trial of andrographolide from Andrographis paniculata was conducted in 13 HIV positive… Expand
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Highly Cited
2000
Highly Cited
2000
Andrographolide, an active component found in leaves of Andrographis paniculata, has been reported to exhibit nitric oxide (NO… Expand
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Highly Cited
1990
Highly Cited
1990
Andrographolide, a diterpenoid lactone, was isolated (yield 0.78% w/w) from A. paniculata (whole plant). Its LD50 in male mice… Expand
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