andrographolide

Known as: (1R-(1-alpha(E(S)),4a-beta,5alpha,6alpha,8a-alpha))-3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-2(3H)-furanone, (3E,4S)-4-hydroxy-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidenedecahydronaphthalen-1-yl]ethylidene}dihydrofuran-2(3H)-one, Andrographis 
A labdane diterpenoid that is produced by the Andrographis paniculata plant, which has a broad range of therapeutic applications including anti… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Nuclear factor-κB (NF-κB) is a central transcriptional factor and a pleiotropic regulator of many genes involved in… (More)
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Review
2012
Review
2012
1. Andrographis paniculata (Burm. f) Nees, commonly known as 'king of bitters', is a herbaceous plant belonging to the Family… (More)
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Highly Cited
2009
Highly Cited
2009
RATIONALE Persistent activation of nuclear factor (NF)-kappaB has been associated with the development of asthma. Andrographolide… (More)
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Highly Cited
2009
Highly Cited
2009
Andrographolide - the major active principle isolated from the plant Andrographis paniculata, has been shown to possess a strong… (More)
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Highly Cited
2004
Highly Cited
2004
Two flavonoids, identified as 5,7,2',3'-tetramethoxyflavanone and 5-hydroxy-7,2',3'-trimethoxyflavone, as well as several other… (More)
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Highly Cited
2002
Highly Cited
2002
We have reported that andrographolide (ANDRO), an active component of Andrographis paniculata, inhibits inflammatory responses by… (More)
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Highly Cited
2000
Highly Cited
2000
A phase I dose-escalating clinical trial of andrographolide from Andrographis paniculata was conducted in 13 HIV positive… (More)
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Highly Cited
2000
Highly Cited
2000
Andrographolide, an active component found in leaves of Andrographis paniculata, has been reported to exhibit nitric oxide (NO… (More)
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Highly Cited
1993
Highly Cited
1993
Andrographolide, the active constituent isolated from the plant Andrographis paniculata, showed a significant dose dependent (0… (More)
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Highly Cited
1990
Highly Cited
1990
Andrographolide, a diterpenoid lactone, was isolated (yield 0.78% w/w) from A. paniculata (whole plant). Its LD50 in male mice… (More)
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