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androgen receptor activity

Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
TOK-001 and abiraterone are potent 17-heteroarylsteroid (17-HAS) inhibitors of Cyp17, one of the rate-limiting enzymes in the… Expand
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Highly Cited
2007
Highly Cited
2007
Prohibitin (PHB) is a cell cycle regulatory protein, known to repress E2F1-mediated gene activation via recruitment of… Expand
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2007
2007
The expression of the WWOX tumor suppressor gene is lost or reduced in a large fraction of various cancers, including prostate… Expand
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Highly Cited
2006
Highly Cited
2006
The androgen receptor (AR) is essential for the growth of prostate cancer cells. Here, we report that tyrosine phosphorylation of… Expand
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2006
2006
The androgen receptor (AR) is a ligand-activated transcription factor that controls growth and survival of prostate cancer cells… Expand
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Highly Cited
2004
Highly Cited
2004
The transcriptional activity of the androgen receptor (AR) is regulated by interaction with various coregulators, one of which is… Expand
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2004
2004
Kinases can phosphorylate and regulate androgen receptor activity during prostate cancer progression. In particular, we showed… Expand
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Highly Cited
2003
Highly Cited
2003
Androgen receptor (AR) is a hormone-regulated transcription factor that mediates a wide array of biological processes including… Expand
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Highly Cited
2002
Highly Cited
2002
The androgen receptor (AR), a member of the nuclear hormone receptor superfamily, is thought to play an important role in the… Expand
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Highly Cited
2001
Highly Cited
2001
Polychlorinated biphenyls (PCBs) are ubiquitous environmental persistent contaminants giving rise to potential health hazard… Expand
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