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androgen receptor activity

Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Androgen ReceptorAndrogen Receptor Regulation Pathway

Narrower (1)

androgen binding

Broader (1)

androgen receptor signaling pathway

Papers overview

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Highly Cited
2012
Highly Cited
2012
Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells.
TOK-001 and abiraterone are potent 17-heteroarylsteroid (17-HAS) inhibitors of Cyp17, one of the rate-limiting enzymes in the… Expand
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Highly Cited
2007
Highly Cited
2007
Prohibitin, a protein downregulated by androgens, represses androgen receptor activity
Prohibitin (PHB) is a cell cycle regulatory protein, known to repress E2F1-mediated gene activation via recruitment of… Expand
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2007
2007
Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling.
The expression of the WWOX tumor suppressor gene is lost or reduced in a large fraction of various cancers, including prostate… Expand
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Highly Cited
2006
Highly Cited
2006
Regulation of androgen receptor activity by tyrosine phosphorylation.
The androgen receptor (AR) is essential for the growth of prostate cancer cells. Here, we report that tyrosine phosphorylation of… Expand
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2006
2006
Receptor-interacting protein 140 is a repressor of the androgen receptor activity.
The androgen receptor (AR) is a ligand-activated transcription factor that controls growth and survival of prostate cancer cells… Expand
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Highly Cited
2004
Highly Cited
2004
Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth
The transcriptional activity of the androgen receptor (AR) is regulated by interaction with various coregulators, one of which is… Expand
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2004
2004
Glycogen Synthase Kinase-3β Is Involved in the Phosphorylation and Suppression of Androgen Receptor Activity*
Kinases can phosphorylate and regulate androgen receptor activity during prostate cancer progression. In particular, we showed… Expand
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Highly Cited
2003
Highly Cited
2003
Regulation of Androgen Receptor Activity by the Nuclear Receptor Corepressor SMRT*
Androgen receptor (AR) is a hormone-regulated transcription factor that mediates a wide array of biological processes including… Expand
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Highly Cited
2002
Highly Cited
2002
Tip60 and Histone Deacetylase 1 Regulate Androgen Receptor Activity through Changes to the Acetylation Status of the Receptor*
The androgen receptor (AR), a member of the nuclear hormone receptor superfamily, is thought to play an important role in the… Expand
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Highly Cited
2001
Highly Cited
2001
Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity.
Polychlorinated biphenyls (PCBs) are ubiquitous environmental persistent contaminants giving rise to potential health hazard… Expand
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