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By treating with histone-deacetylase inhibitor valproate sodium, three new heterdimeric tetrahydroxanthone–chromanone lactones… Expand Penicillium roqueforti is used in the production of several kinds of ripened blue-veined cheeses. In addition, this fungus… Expand Penicillium roqueforti is a filamentous fungus involved in the ripening of several kinds of blue cheeses. In addition, this… Expand Fungi have long been regarded as rich sources of novel bioactive natural products. The 20th century has witnessed the discovery… Expand High quality local varieties of blue-veined cheese are made in the villages of the valleys of Cabrales, Valdeón and Bejes… Expand Secondary metabolites produced by Penicillium paneum and Penicillium roqueforti from baled grass silage were analyzed. A total of… Expand This is the first finding of andrastins in blue cheese as well as any other sample type. Here, they were produced by the… Expand In the course of our screening for compounds that reverse multidrug resistance, we found that the cytotoxicity of vincristine was… Expand androstane skeleton with a keto-enol tautomerism at the cyclopentane ring. Wecarried out further isolation for PFTase inhibitors… Expand The structures of new protein farnesyltransferase inhibitors, andrastins A-C, were elucidated. The cyclopentane ring of… Expand