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andexanet

 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Background Andexanet alfa is a modified recombinant inactive form of human factor Xa developed for reversal of factor Xa… Expand
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2019
2019
Andexanet alfa is a recombinant factor Xa decoy molecule capable of reversing direct and indirect factor Xa-inhibiting… Expand
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Review
2019
Review
2019
The direct oral anticoagulants (DOACs) have gained popularity recently among both patients and providers for their comparable or… Expand
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2018
2018
Introduction Increasing use of factor Xa (FXa) inhibitors necessitates effective reversal agents to manage bleeding. Andexanet… Expand
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2018
2018
Anticoagulants such as unfractionated heparin (UFH), low-molecular-weight heparins (LMWHs), fondaparinux, and direct oral… Expand
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2018
2018
Oral fostamatinib is an orally administered small molecule spleen tyrosine kinase (SYK) inhibitor approved for the treatment of… Expand
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2017
2017
Direct factor Xa (FXa) inhibitors lack a specific reversal agent for emergencies such as major bleeding or urgent surgery… Expand
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2017
2017
Essentials There is currently no approved reversal agent for factor Xa (FXa) inhibitors Andexanet alfa has been developed to… Expand
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2016
2016
The need for oral anticoagulation is rising to combat an increasing prevalence of atrial fibrillation and venous thromboembolism… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Bleeding is a complication of treatment with factor Xa inhibitors, but there are no specific agents for the reversal… Expand
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