amyloid fibril formation

Known as: amyloid fibril assembly 
The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. An example of this is seen… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2018
0204019702018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Many globular and natively disordered proteins can convert into amyloid fibrils. These fibrils are associated with numerous… (More)
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Highly Cited
2007
Highly Cited
2007
The formation of amyloid fibrils is a common biochemical characteristic that occurs in Alzheimer's disease and several other… (More)
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2007
2007
The lack of understanding of amyloid fibril formation at the molecular level is a major obstacle in devising strategies to… (More)
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Highly Cited
2006
Highly Cited
2006
In Alzheimer's disease, both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) colocalize with brain fibrils of… (More)
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Highly Cited
2005
Highly Cited
2005
The molecular structure of the amyloid fibril has remained elusive because of the difficulty of growing well diffracting crystals… (More)
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Highly Cited
2004
Highly Cited
2004
The establishment of rules that link sequence and amyloid feature is critical for our understanding of misfolding diseases. To… (More)
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Highly Cited
1996
Highly Cited
1996
Transthyretin (TTR) amyloid fibril formation is observed systemically in familial amyloid polyneuropathy and senile systemic… (More)
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Highly Cited
1995
Highly Cited
1995
A central issue in the pathogenesis of Alzheimer's disease (AD) is the relationship between amyloid deposition and… (More)
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Highly Cited
1992
Highly Cited
1992
Amyloid diseases are caused by the self-assembly of a given protein into an insoluble cross-beta-sheet quaternary structural form… (More)
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Highly Cited
1990
Highly Cited
1990
Islet amyloid polypeptide (IAPP), a putative polypeptide hormone, is a product of pancreatic beta-cells and the major constituent… (More)
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