amotosalen

A synthetic psoralen, light-activated DNA and RNA crosslinking agent, with protective activity against pathogens such as bacteria, viruses, protozoa… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) transmitted by mosquitoes. The potential for ZIKV… (More)
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2015
2015
BACKGROUND Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination… (More)
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2014
2014
BACKGROUND Dengue virus (DENV) is the most prevalent arbovirus in tropical and subtropical regions. Transfusion-transmitted DENV… (More)
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2006
2006
BACKGROUND Pathogen inactivation of plasma intended for transfusion is now the standard of care in Belgium. Two methods for… (More)
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2006
2006
BACKGROUND The INTERCEPT Blood System, a photochemical treatment (PCT) process, has been developed to inactivate pathogens in… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Viral contamination of platelet (PLT) concentrates can result in transfusion-transmitted diseases. A photochemical… (More)
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2005
2005
BACKGROUND A photochemical treatment (PCT) method utilizing a novel psoralen, amotosalen HCl, with ultraviolet A illumination has… (More)
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2004
2004
BACKGROUND Bacterial contamination of platelet (PLT) concentrates can result in transfusion-transmitted sepsis. A photochemical… (More)
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2004
2004
BACKGROUND A photochemical treatment (PCT) method to inactivate pathogens in platelet concentrates has been developed. The system… (More)
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Highly Cited
2003
Highly Cited
2003
A nucleic acid-targeted photochemical treatment (PCT) using amotosalen HCl (S-59) and ultraviolet A (UVA) light was developed to… (More)
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