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amotosalen hydrochloride

The hydrochloride salt form of amotosalen, a synthetic psoralen and light-activated DNA, RNA crosslinking agent, with protective activity against… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Ebola virus disease is a public health emergency of international concern, and enormous efforts are being made in the development… Expand
2015
2015
Several plasma pathogen reduction technologies (PRT) are currently available. We evaluated three plasma PRT processes: Cerus… Expand
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Highly Cited
2008
Highly Cited
2008
Upon exposure to UVA light, psoralens can induce DNA interstrand cross-links (ICLs), which can block DNA replication and… Expand
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Review
2006
Review
2006
Both fresh frozen plasma (FFP) and platelets are heavily used in massive transfusion. Although FFP can partially correct abnormal… Expand
2005
2005
BACKGROUND: The standard treatment for thrombotic thrombocytopenic purpura (TTP) is plasma exchange with fresh‐frozen plasma (FFP… Expand
2004
2004
BACKGROUND:  A photochemical treatment (PCT) process utilizing amotosalen hydrochloride and long wavelength UVA light has been… Expand
Highly Cited
2002
Highly Cited
2002
BACKGROUND : To date, no clinical trials have characterized FFP infusion efficacy, and infusion still carries infectious risk… Expand
Review
2001
Review
2001
Psoralens plus ultraviolet A (UVA) light inactivate viruses and bacteria as well as leukocytes. A system employing the synthetic… Expand
Review
2001
Review
2001
  • N. Luban
  • Seminars in hematology
  • 2001
  • Corpus ID: 29604121
Patients with hematological malignancies and infants with congenital immunodeficiencies who received blood are two of many… Expand
Review
2001
Review
2001
  • L. Lin
  • Seminars in hematology
  • 2001
  • Corpus ID: 25911405
Cytomegalovirus (CMV) infection in immunocompromised patients may result in severe morbidity and mortality. The standard of care… Expand