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Ebola virus disease is a public health emergency of international concern, and enormous efforts are being made in the development… Expand Several plasma pathogen reduction technologies (PRT) are currently available. We evaluated three plasma PRT processes: Cerus… Expand Upon exposure to UVA light, psoralens can induce DNA interstrand cross-links (ICLs), which can block DNA replication and… Expand Both fresh frozen plasma (FFP) and platelets are heavily used in massive transfusion. Although FFP can partially correct abnormal… Expand BACKGROUND: The standard treatment for thrombotic thrombocytopenic purpura (TTP) is plasma exchange with fresh‐frozen plasma (FFP… Expand BACKGROUND: A photochemical treatment (PCT) process utilizing amotosalen hydrochloride and long wavelength UVA light has been… Expand BACKGROUND : To date, no clinical trials have characterized FFP infusion efficacy, and infusion still carries infectious risk… Expand Psoralens plus ultraviolet A (UVA) light inactivate viruses and bacteria as well as leukocytes. A system employing the synthetic… Expand Patients with hematological malignancies and infants with congenital immunodeficiencies who received blood are two of many… Expand Cytomegalovirus (CMV) infection in immunocompromised patients may result in severe morbidity and mortality. The standard of care… Expand