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amotosalen hydrochloride

The hydrochloride salt form of amotosalen, a synthetic psoralen and light-activated DNA, RNA crosslinking agent, with protective activity against… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2015
012320012015

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amotosalen

Related mentions per year

Related mentions per year

2001-2018
20002005201020152020
amotosalen hydrochloride
amotosalen

Papers overview

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2016
2016
In-Silico Analysis of Amotosalen Hydrochloride Binding to CD-61 of Platelets.
OBJECTIVE To determine the docking of Amotosalen hydrochloride (AH) at CD-61 of platelets, and to suggest the cause of bleeding… (More)
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2016
2016
Composition of growth factors and cytokines in lysates obtained from fresh versus stored pathogen-inactivated platelet units.
BACKGROUND Platelet lysate is a readily available source of growth factors, and other mediators, which has been used in a variety… (More)
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2016
2016
Pathogen-reduced Ebola virus convalescent plasma: first steps towards standardization of manufacturing and quality control including assessment of Ebola-specific neutralizing antibodies.
BACKGROUND Ebola virus disease is a public health emergency of international concern, and enormous efforts are being made in the… (More)
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2015
2015
Quantitative analysis of plasma proteins in whole blood-derived fresh frozen plasma prepared with three pathogen reduction technologies.
Several plasma pathogen reduction technologies (PRT) are currently available. We evaluated three plasma PRT processes: Cerus… (More)
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2008
2008
Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation.
Upon exposure to UVA light, psoralens can induce DNA interstrand cross-links (ICLs), which can block DNA replication and… (More)
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Review
2006
Review
2006
Risks of fresh frozen plasma and platelets.
Both fresh frozen plasma (FFP) and platelets are heavily used in massive transfusion. Although FFP can partially correct abnormal… (More)
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2005
2005
Coagulation factor levels in cryosupernatant prepared from plasma treated with amotosalen hydrochloride (S-59) and ultraviolet A light.
BACKGROUND The standard treatment for thrombotic thrombocytopenic purpura (TTP) is plasma exchange with fresh-frozen plasma (FFP… (More)
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2004
2004
Photochemical treatment of platelet concentrates with amotosalen hydrochloride and ultraviolet A light inactivates free and latent cytomegalovirus in a murine transfusion model.
BACKGROUND A photochemical treatment (PCT) process utilizing amotosalen hydrochloride and long wavelength UVA light has been… (More)
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2003
2003
Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59.
  • BioDrugs : clinical immunotherapeutics…
  • 2003
Adis CommentsCerus Corporation is developing a variety of pathogen-inactivation systems, based on its Helinx technology. Three of… (More)
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2002
2002
Pharmacokinetic study of FFP photochemically treated with amotosalen (S-59) and UV light compared to FFP in healthy volunteers anticoagulated with warfarin.
BACKGROUND To date, no clinical trials have characterized FFP infusion efficacy, and infusion still carries infectious risk. This… (More)
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