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aminoimidazole ribotide
Known as:
1H-imidazol-5-amine, 1-(5-O-phosphono-beta-D-ribofuranosyl)
, 5-amino-1-ribofuranosylimidazole 5'-phosphate
, 5-aminoimidazole ribotide
National Institutes of Health
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Related topics
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1 relation
Broader (1)
Ribonucleotides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
A. Pelet
,
V. Škopová
,
+14 authors
M. Zikánová
Human molecular genetics
2019
Corpus ID: 204244284
We report for the first time an autosomal recessive inborn error of de novo purine synthesis (DNPS)-PAICS deficiency. We…
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2018
2018
An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12.
Derek M Gagnon
,
T. A. Stich
,
Angad P Mehta
,
Sameh H. Abdelwahed
,
T. Begley
,
R. D. Britt
Journal of the American Chemical Society
2018
Corpus ID: 207192297
Organisms that perform the de novo biosynthesis of cobalamin (vitamin B12) do so via unique pathways depending on the presence of…
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2015
2015
Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.
Angad P Mehta
,
Sameh H. Abdelwahed
,
+5 authors
T. Begley
Journal of the American Chemical Society
2015
Corpus ID: 207155599
Comparative genomics of the bacterial thiamin pyrimidine synthase (thiC) revealed a paralogue of thiC (bzaF) clustered with…
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2015
2015
Aminoimidazole Carboxamide Ribotide Exerts Opposing Effects on Thiamine Synthesis in Salmonella enterica
Jannell V. Bazurto
,
N. Heitman
,
D. Downs
Journal of bacteriology
2015
Corpus ID: 40910622
ABSTRACT In Salmonella enterica, the thiamine biosynthetic intermediate 5-aminoimidazole ribotide (AIR) can be synthesized de…
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2006
2006
A connection between iron-sulfur cluster metabolism and the biosynthesis of 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate in Salmonella enterica.
Michael J. Dougherty
,
D. Downs
Microbiology
2006
Corpus ID: 41838677
Several cellular pathways have been identified which affect the efficiency of thiamine biosynthesis in Salmonella enterica…
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Highly Cited
1998
Highly Cited
1998
The apbE Gene Encodes a Lipoprotein Involved in Thiamine Synthesis in Salmonella typhimurium
B. Beck
,
D. Downs
Journal of bacteriology
1998
Corpus ID: 45443332
ABSTRACT Thiamine pyrophosphate is an essential cofactor that is synthesized de novo in Salmonella typhimurium. The biochemical…
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1997
1997
Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium
B. Beck
,
L. Connolly
,
A. De Las Peñas
,
D. Downs
Journal of bacteriology
1997
Corpus ID: 27113441
In Salmonella typhimurium, the genetic loci and biochemical reactions necessary for the conversion of aminoimidazole ribotide…
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Highly Cited
1996
Highly Cited
1996
Genetic analysis of metabolic crosstalk and its impact on thiamine synthesis in Salmonella typhimurium.
L. Petersen
,
J. Enos-Berlage
,
D. Downs
Genetics
1996
Corpus ID: 5818723
The first five steps in de novo purine biosynthesis are involved in the formation of the 4-amino-5-hydroxymethyl-2-methyl…
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1992
1992
Evidence for a new, oxygen-regulated biosynthetic pathway for the pyrimidine moiety of thiamine in Salmonella typhimurium
D. Downs
Journal of bacteriology
1992
Corpus ID: 5309182
The synthesis of the pyrimidine moiety of thiamine (vitamin B1) shares five reactions with the de novo purine biosynthetic…
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1956
1956
SYNTHESIS OF PURINE INTERMEDIATES BY A CELL-FREE EXTRACT OF ESCHERICHIA COLI
S. Love
Journal of bacteriology
1956
Corpus ID: 2548063
A purine-requiring mutant (strain W-11) of Escherichia coli strain K-12, has been shown to synthesize 5-aminoimidazole riboside…
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