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aminoimidazole ribotide

Known as: 1H-imidazol-5-amine, 1-(5-O-phosphono-beta-D-ribofuranosyl), 5-amino-1-ribofuranosylimidazole 5'-phosphate, 5-aminoimidazole ribotide 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Ribonucleotides

Papers overview

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2019
2019
PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
We report for the first time an autosomal recessive inborn error of de novo purine synthesis (DNPS)-PAICS deficiency. We… Expand
2018
2018
An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12.
  • Derek M Gagnon, Troy A Stich, Angad P Mehta, Sameh H Abdelwahed, Tadhg P Begley, R David Britt
  • Journal of the American Chemical Society
  • 2018
    • Corpus ID: 207192297
Organisms that perform the de novo biosynthesis of cobalamin (vitamin B12) do so via unique pathways depending on the presence of… Expand
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2015
2015
Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.
Comparative genomics of the bacterial thiamin pyrimidine synthase (thiC) revealed a paralogue of thiC (bzaF) clustered with… Expand
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2015
2015
Aminoimidazole Carboxamide Ribotide Exerts Opposing Effects on Thiamine Synthesis in Salmonella enterica.
UNLABELLED In Salmonella enterica, the thiamine biosynthetic intermediate 5-aminoimidazole ribotide (AIR) can be synthesized de… Expand
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2012
2012
Analysis of ThiC variants in the context of the metabolic network of Salmonella enterica.
In bacteria, the 4-amino-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine is synthesized from 5-aminoimidazole ribotide… Expand
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2006
2006
A connection between iron-sulfur cluster metabolism and the biosynthesis of 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate in Salmonella enterica.
Several cellular pathways have been identified which affect the efficiency of thiamine biosynthesis in Salmonella enterica… Expand
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Highly Cited
1998
Highly Cited
1998
The apbE gene encodes a lipoprotein involved in thiamine synthesis in Salmonella typhimurium.
Thiamine pyrophosphate is an essential cofactor that is synthesized de novo in Salmonella typhimurium. The biochemical steps and… Expand
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1997
1997
Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium.
In Salmonella typhimurium, the genetic loci and biochemical reactions necessary for the conversion of aminoimidazole ribotide… Expand
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Highly Cited
1996
Highly Cited
1996
Genetic analysis of metabolic crosstalk and its impact on thiamine synthesis in Salmonella typhimurium.
The first five steps in de novo purine biosynthesis are involved in the formation of the 4-amino-5-hydroxymethyl-2-methyl… Expand
1992
1992
Evidence for a new, oxygen-regulated biosynthetic pathway for the pyrimidine moiety of thiamine in Salmonella typhimurium.
  • D. Downs
  • Journal of bacteriology
  • 1992
    • Corpus ID: 5309182
The synthesis of the pyrimidine moiety of thiamine (vitamin B1) shares five reactions with the de novo purine biosynthetic… Expand
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