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alpha1-adrenergic receptor activity

Known as: alpha1 adrenoceptor 
Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Priapism Associated With Antipsychotics: Role of &agr;1 Adrenoceptor Affinity
Case reports indicate that antipsychotics can cause priapism, a persistent penile erection possibly leading to erectile… Expand
Highly Cited
2007
Highly Cited
2007
Catecholaminergic Control of Mitogen-Activated Protein Kinase Signaling in Paraventricular Neuroendocrine Neurons In Vivo and In Vitro: A Proposed Role during Glycemic Challenges
Paraventricular hypothalamic (PVH) corticotropin-releasing hormone (CRH) neuroendocrine neurons mount neurosecretory and… Expand
Highly Cited
2006
Highly Cited
2006
Critical Involvement of Dopaminergic Neurotransmission in Impulsive Decision Making
BACKGROUND Impulsive decision making, apparent as intolerance for reinforcement delay, is prominent in attention-deficit… Expand
Highly Cited
2005
Highly Cited
2005
Evidence for the presence of α1 adrenoceptor subtypes in the human ureter
Several studies have proposed a role for α1 adrenoceptors (ARs) in ureteral physiology, indicating that they are present in the… Expand
Highly Cited
2004
Highly Cited
2004
Phox2a Gene, A6 Neurons, and Noradrenaline Are Essential for Development of Normal Respiratory Rhythm in Mice
Although respiration is vital to the survival of all mammals from the moment of birth, little is known about the genetic factors… Expand
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Highly Cited
2004
Highly Cited
2004
Noradrenergic Inhibition of Midbrain Dopamine Neurons
Receptors that couple to phosphoinositide hydrolysis, which include metabotropic glutamate receptors (mGluRs) and muscarinic… Expand
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Highly Cited
2003
Highly Cited
2003
Priming of Excitatory Synapses by α1 Adrenoceptor-Mediated Inhibition of Group III Metabotropic Glutamate Receptors
Adaptive responses mediated by the hypothalamus require sustained activation until homeostasis is achieved. Increases in… Expand
Highly Cited
2000
Highly Cited
2000
Serotonergic dorsal raphe neurons cease firing by disfacilitation during paradoxical sleep
Using in vivo extracellular unit recordings combined with microdialysis infusion in the cat, we found that the cessation of… Expand
Highly Cited
1999
Highly Cited
1999
alpha1-ADRENOCEPTOR ANTAGONISTS TERAZOSIN AND DOXAZOSIN INDUCE PROSTATE APOPTOSIS WITHOUT AFFECTING CELL PROLIFERATION IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA
AbstractPurpose: Recent evidence indicated that an alpha1 blocker, doxazosin, induces prostate apoptosis in patients with benign… Expand
1998
1998
Characterisation of the cardiovascular pharmacology of medetomidine in the horse and sheep.
Medetomidine was administered to sheep and horses at a dose rate of 5 microg kg(-1) (i.v.). Heart rate and blood pressure were… Expand
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